Inventors:
Jingxin Qiu - Buffalo NY, US
Mingli Yang - Gainesville FL, US
David A. Ostrov - Gainesville FL, US
W. Stratford May - Gainesville FL, US
Assignee:
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION - Gainesville FL
International Classification:
A61K 39/395, A61K 31/17, A61K 31/4188, A61K 31/713, A61K 31/7088, C12N 5/09, C12Q 1/02, C12Q 1/18, G01N 33/68, A61K 48/00, A61P 35/00, A61P 35/02, G06G 7/58
US Classification:
4241741, 514596, 514598, 514393, 514 44 A, 435375, 435 29, 435 32, 435 71, 514 44 R, 703 11
Abstract:
The invention provides compositions and methods for the treatment of neoplasias that are cytotoxic to neoplastic cells or that modulate JAZ expression, subcellular localization, or biological activity.