Jin Kyung Kim
Engineers in Salt Lake City, UT
License number
Utah 343793-2202
Category
Engineer/Land Surveyor
Type
Professional Engineer
Address
Address
Salt Lake City, UT
Professional information
Aliphatically Modified Biodegradable Block Copolymers As Thermogelling Polymers
US Patent:
7740877, Jun 22, 2010
Filed:
Apr 6, 2007
Appl. No.:
11/784528
Inventors:
Sung Wan Kim - Salt Lake City UT, US
Seongbong Jo - Salt Lake City UT, US
Jin Kim - Salt Lake City UT, US
Seongbong Jo - Salt Lake City UT, US
Jin Kim - Salt Lake City UT, US
Assignee:
University of Utah Research Foundation - Salt Lake City UT
International Classification:
A61F 2/02, C08G 63/08
US Classification:
424426, 528354
Abstract:
A thermogelling, aliphatically modified polymer for use in drug delivery is described. Illustrative embodiments include poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone) hexanoate and poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone) laurate. Another illustrative embodiment includes a composition having a thermogelling amount of an aliphatically modified poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone) and an effective amount of a drug. The thermogelling polymers are made by bonding an aliphatic group to poly(lactic-co-ε-caprolactone)-poly(ethylene glycol)-poly(lactic-co-ε-caprolactone). A method of use includes injecting a warm-blooded individual with a thermogelling amount of the aliphatically modified polymer and a drug.