Inventors:
C. Kahn - West Newton MA, US
Jianhua Zhu - Bowling Green KY, US
International Classification:
A61K048/00, A61K031/00
Abstract:
The present invention is based on the discovery of a novel bimolecular, bidirectional mechanism of regulation between nm23 and Rad. Accordingly, the present invention provides a method of modulating an activity of nm23 in a subject at risk for a proliferative disorder, comprising: modulating the level of Rad activity.