Inventors:
Griffin Rodgers - Kensington MD, US
Wen-Li Liu - Rockville MD, US
Jiachang Zhang - Bakersfield CA, US
International Classification:
A01K067/027, C12Q001/68, G01N033/574, C07H021/04
US Classification:
800018000, 435006000, 435007230, 435069300, 435320100, 435325000, 530395000, 530388800, 536023500
Abstract:
An isolated acid having the sequence of a) SEQ ID NO: 1; b) the sequence of SEQ ID NO: 2; c) the sequence of SEQ ID NO: 3; d) a sequence complementary to any of a), b), or c); or e) a sequence of at least 10 contiguous nucleotides specific for any of a)-d). The invention relates to the identification and characterization of a hitherto unidentified human gene, hGC-1. The protein encoded by hGC-1 appears to be a member of the olfactomedin-related proteins. The invention relates generally to the gene (hGC-1), nucleic acids, cDNA, vectors, polypeptides, protein, antibodies, cells, transgenic animal, and other compositions related to hGC-1. Additionally, primers are provided for identifying hGC-1. The invention further relates to methods of using these compositions, such as diagnosis and treatment of various cancers, and kits comprising these compositions.