JERRY R MENDELL, MD
Neurology at Childrens Dr, Columbus, OH
License number
Ohio 35035346
Category
Neurology
Type
Neurology
Address
Address
700 Childrens Dr, Columbus, OH 43205
Phone
(614) 355-3574
(614) 722-3273 (Fax)
(614) 722-3273 (Fax)
Professional information
Dr. Jerry R Mendell, Columbus OH - MD (Doctor of Medicine)
Specialties:
Neurology, Neuropsychiatry (Neurology)
Address:
Nationwide Children's Hospital, Research II - Rm WA3011
700 Childrens Dr Suite Suite: STE STE, Columbus 43205
(614) 722-2203 (Phone)
700 Childrens Dr Suite Suite: STE STE, Columbus 43205
(614) 722-2203 (Phone)
Certifications:
Neurology, 1972
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Nationwide Children's Hospital, Research II - Rm WA3011
700 Childrens Dr Suite Suite: STE STE, Columbus 43205
Wexner Medical Center at The Ohio State University
410 West 10Th Ave, Columbus 43210
James Cancer Hospital and Solove Research Institute
300 West 10Th Ave, Columbus 43210
Nationwide Children's Hospital
700 Dr Children's, Columbus 43205
700 Childrens Dr Suite Suite: STE STE, Columbus 43205
Wexner Medical Center at The Ohio State University
410 West 10Th Ave, Columbus 43210
James Cancer Hospital and Solove Research Institute
300 West 10Th Ave, Columbus 43210
Nationwide Children's Hospital
700 Dr Children's, Columbus 43205
Education:
Medical School
University Of Texas Southwestern Medical Center At Dallas
Graduated: 1966
Columbia Presby Med Center
Graduated: 1967
National Institute Of Health
Graduated: 1970
Ny Neur Institute
Graduated: 1969
Graduated: 1972
University Of Texas Southwestern Medical Center At Dallas
Graduated: 1966
Columbia Presby Med Center
Graduated: 1967
National Institute Of Health
Graduated: 1970
Ny Neur Institute
Graduated: 1969
Graduated: 1972
Jerry R Mendell, Columbus OH
Specialties:
Neurologist
Address:
555 S 18Th St, Columbus, OH 43205
Education:
University of Texas, Southwestern Medical School (Dallas) - Doctor of Medicine
National Institutes of Health-Clinical Center - Fellowship - Neuromuscular Disorders
National Institutes of Health-Clinical Center - Residency - Neurology
New York State Psychiatric Institute - Residency - Neurology
National Institutes of Health-Clinical Center - Fellowship - Neuromuscular Disorders
National Institutes of Health-Clinical Center - Residency - Neurology
New York State Psychiatric Institute - Residency - Neurology
Board certifications:
American Board of Psychiatry and Neurology Certification in Neurology (Psychiatry and Neurology)
Jerry R Mendell, Columbus OH
Specialties:
Neurology, Pediatric Neurodevelopmental Disabilities
Work:
The Research Institute at Nationwide Children's Hospital
700 Childrens Dr, Columbus, OH 43205 The Ohio State University
1654 Upham Dr, Columbus, OH 43210
700 Childrens Dr, Columbus, OH 43205 The Ohio State University
1654 Upham Dr, Columbus, OH 43210
Education:
The University of Texas Southwestern (1966)
Director Of Gene Therapy At Nationwide Childrens Hospital
Location:
Columbus, Ohio Area
Industry:
Research
Experience:
Nationwide Childrens Hospital (Non-Profit; 5001-10,000 employees; Research industry): Director of Gene Therapy, (-)
Myostatin Inhibition For Enhancing Muscle And/Or Improving Muscle Function
US Patent:
2010017, Jul 15, 2010
Filed:
Nov 29, 2007
Appl. No.:
12/516995
Inventors:
Brian K. Kaspar - Westerville OH, US
Jerry R. Mendell - Columbus OH, US
Jerry R. Mendell - Columbus OH, US
Assignee:
Nationwide Children's Hospital - Columbus OH
International Classification:
A61K 9/14, A61K 35/76, C07H 21/00, C12N 7/01, C12N 5/071, C07H 21/04, A61P 21/00
US Classification:
424489, 424 932, 536 2372, 4352351, 435325
Abstract:
The present invention relates to methods for inhibiting myostatin, a regulator of muscle mass, for muscle enhancement (including inducing hypertrophy and/or hyperplasia) as well as improving muscle function (including decreasing atrophy and/or increasing endurance, force and/or strength). The methods involve delivering genes to cells using gene delivery in order to inhibit myostatin. Examples of genes to be delivered are genes encoding’ proteins such as Follistatin, Follistatin-related gene-1 (FLRG-I), growth differentiation factor associated protein-1 (GASP-I) and myostatin precursor propeptide. The genes are delivered using a recombinant Adeno-associated virus (rAAV) lacking rep and cap DNA capable of infecting the cells. Following introduction, the genes are expressed in the cell body of the infected cell and the encoded proteins are secreted systemically. In other methods-of the invention expression of proteins such as activin lib and myostatin is inhibited by oligonucleotide techniques to effect muscle enhancement. All the methods have applications in the treatment of musculoskeletal and neurodegenerative disorders among others, as well as enhancing muscle in livestock.
Compositions And Methods For Treating Hepatic Neoplasia
US Patent:
2011030, Dec 8, 2011
Filed:
Dec 2, 2009
Appl. No.:
13/132783
Inventors:
Joshua T. Mendell - Dallas TX, US
Kathryn A. Mendell - Baltimore MD, US
Raghu R. Chivukula - Baltimore MD, US
Erik A. Wentzel - Leesburg VA, US
Jerry R. Mendell - Columbus OH, US
K. Reed Clark - Westerville OH, US
Janaiah Kota - Columbus OH, US
Kathryn A. Mendell - Baltimore MD, US
Raghu R. Chivukula - Baltimore MD, US
Erik A. Wentzel - Leesburg VA, US
Jerry R. Mendell - Columbus OH, US
K. Reed Clark - Westerville OH, US
Janaiah Kota - Columbus OH, US
Assignee:
Nationwide Children's Hospital, Inc - Columbus OH
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
International Classification:
A61K 48/00, C12N 15/85, C12N 15/86, A61P 1/16, C12N 5/10, C12Q 1/68, A61P 35/00, C12N 5/09, C12N 15/861
US Classification:
514 44 R, 435375, 4353201, 435325, 435 611, 435 613
Abstract:
The present invention provides compositions and methods featuring miR-26 microRNA polynucleotides for the diagnosis, treatment or prevention of hepatic neoplasia.