Inventors:
Massoud Akhtari - Pasadena CA, US
Jerome Engel - Los Angeles CA, US
International Classification:
A61K 49/06, A61K 49/14, A61K 49/10, A61K 49/04, A61K 31/175, A61K 36/18, A61K 31/56, A61P 35/00, B82Y 5/00
US Classification:
424 934, 424 93, 424 935, 424 94, 424 943, 424 944, 514589, 424725, 514169, 977773, 977906, 977930, 977928
Abstract:
The present invention provides methods of detecting a cancer cell in an individual, methods of grading a cancer, and methods of treating a cancer. The methods involve use of functionalized magnetic nanoparticles that comprise a moiety that provides for selective association with, and/or metabolic uptake into, a cancer cell.