Inventors:
Jerome B. Zeldis - Princeton NJ, US
Assignee:
CELGENE CORPORATION - Warren NJ
International Classification:
A61K 38/20, A61K 39/395, A61K 38/16, A61K 31/56, A61K 31/5377, A61K 31/517, A61K 31/352, A61K 38/21, A61P 35/00, A61K 31/404, A61K 38/13, A61K 31/65, A61K 31/69, A61K 31/4353, A61K 31/704
US Classification:
424 852, 4241521, 4241381, 4241581, 4241411, 514 12, 514178, 514182, 5142345, 5142664, 4241331, 4241451, 514453, 514415, 514 9, 514154, 514 64, 514283, 514 34, 424 854, 514416
Abstract:
Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of a selective cytokine inhibitory drug alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of a selective cytokine inhibitory drug. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.