JENS UWE PONIKAU
Pilots at Lebrun Cir, Amherst, NY
License number
New York A4452667
Issued Date
Aug 2016
Expiration Date
Aug 2018
Category
Airmen
Type
Authorized Aircraft Instructor
Address
Address
36 Lebrun Cir, Amherst, NY 14226
Professional information
Fungus-Induced Inflammation And Eosinophil Degranulation
US Patent:
7887820, Feb 15, 2011
Filed:
Jul 13, 2010
Appl. No.:
12/835592
Inventors:
Hirohito Kita - Rochester MN, US
Jens Ponikau - Amherst NY, US
Christopher B. Lawrence - Blacksburg VA, US
Jens Ponikau - Amherst NY, US
Christopher B. Lawrence - Blacksburg VA, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
Virginia Tech Intellectual Properties, Inc. - Blacksburg VA
Virginia Tech Intellectual Properties, Inc. - Blacksburg VA
International Classification:
A61K 39/00
US Classification:
4242741, 424 941, 4241851, 530350, 435183
Abstract:
This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for assessing eosinophil degranulation, and methods for identifying inhibitors of fungus-induced inflammation and/or eosinophil degranulation are provided.
Methods And Materials For Treating And Preventing Inflammation Of Mucosal Tissue
US Patent:
2009025, Oct 8, 2009
Filed:
May 13, 2009
Appl. No.:
12/465394
Inventors:
Jens Ponikau - Amherst NY, US
International Classification:
A61K 31/7048, A61P 11/06, A61P 11/02, A61P 31/10
US Classification:
514 28
Abstract:
The invention involves methods and materials for treating and preventing non-invasive fungus-induced mucositis. Specifically, the invention involves administrating an antifungal agent such that it contact mucus in an amount, at a frequency, and for a duration effective to prevent, reduce, or eliminate non-invasive fungus-induced rhinosinusitis. This invention also provides methods and materials for diagnosing non-invasive fungus-induced rhinosinusitis and culturing non-invasive fungus from a mammalian mucus sample as well as specific antifungal formulations and medical devices for treating and preventing non-invasive fungus-induced rhinosinusitis. In addition, the invention provides methods and materials for treating and preventing other non-invasive fungus-induced mucositis conditions such as chronic otitis media, chronic colitis, and Crohn's disease. Further, the invention involves methods and materials for treating and preventing chronic asthma symptoms.
Fungus-Induced Inflammation And Eosinophil Degranulation
US Patent:
7972611, Jul 5, 2011
Filed:
Dec 20, 2010
Appl. No.:
12/973100
Inventors:
Hirohito Kita - Rochester MN, US
Jens Ponikau - Amherst NY, US
Christopher Lawrence - Blackburg VA, US
Jens Ponikau - Amherst NY, US
Christopher Lawrence - Blackburg VA, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
Virginia Tech Intellectual Properties, Inc. - Blacksburg VA
Virginia Tech Intellectual Properties, Inc. - Blacksburg VA
International Classification:
A61K 39/00
US Classification:
4242741, 4241851, 424 941, 435183, 530350
Abstract:
This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for assessing eosinophil degranulation, and methods for identifying inhibitors of fungus-induced inflammation and/or eosinophil degranulation are provided.
Fungus-Induced Inflammation And Eosinophil Degranulation
US Patent:
7662400, Feb 16, 2010
Filed:
Oct 13, 2006
Appl. No.:
11/580454
Inventors:
Hirohito Kita - Rochester MN, US
Jens Ponikau - Amherst NY, US
Christopher Lawrence - Blacksburg VA, US
Jens Ponikau - Amherst NY, US
Christopher Lawrence - Blacksburg VA, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
Virginia Tech Intellectual Properties, Inc. - Blacksburg VA
Virginia Tech Intellectual Properties, Inc. - Blacksburg VA
International Classification:
A61K 39/00
US Classification:
4242741, 424 941, 4241851, 530350, 435183
Abstract:
This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for assessing eosinophil degranulation, and methods for identifying inhibitors of fungus-induced inflammation and/or eosinophil degranulation are provided.
Fungus-Induced Inflammation And Eosinophil Degranulation
US Patent:
7815919, Oct 19, 2010
Filed:
Dec 2, 2009
Appl. No.:
12/629638
Inventors:
Hirohito Kita - Rochester MN, US
Jens Ponikau - Amherst NY, US
Christopher B. Lawrence - Blacksburg VA, US
Jens Ponikau - Amherst NY, US
Christopher B. Lawrence - Blacksburg VA, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
Virginia Tech Intellectual Properties, Inc. - Blacksburg VA
Virginia Tech Intellectual Properties, Inc. - Blacksburg VA
International Classification:
A61K 39/00
US Classification:
4242741, 424 941, 4241851, 530350, 435183
Abstract:
This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for assessing eosinophil degranulation, and methods for identifying inhibitors of fungus-induced inflammation and/or eosinophil degranulation are provided.
Detecting A Bacterial Process In Chronic Rhinosinusitis
US Patent:
2010009, Apr 22, 2010
Filed:
Dec 18, 2009
Appl. No.:
12/641868
Inventors:
Jens Ponikau - Amherst NY, US
David Sherris - Buffalo NY, US
Hirohito Kita - Rochester MN, US
David Sherris - Buffalo NY, US
Hirohito Kita - Rochester MN, US
International Classification:
G01N 33/573, C12Q 1/44, C12Q 1/28
US Classification:
435 74, 435 19, 435 28
Abstract:
The present invention provides a method for identifying bacterial induced rhinosinusitis. The method comprises obtaining a nasal or paranasal mucus sample and detecting the presence of neutrophil degranulation in the mucus sample. Degranulation of neutrophils can be determined by morphological analysis of the cells in the mucus or by detection of released (i.e., “free”) granule content markers such as neutrophil elastase or myeloperoxidase. Based on an accurate determination of the cause of sinusitis as described herein, an appropriate treatment can be instituted.
Detecting A Bacterial Process In Chronic Rhinosinusitis
US Patent:
7659080, Feb 9, 2010
Filed:
Aug 30, 2007
Appl. No.:
11/897494
Inventors:
Jens Ponikau - Amherst NY, US
David Sherris - Buffalo NY, US
Hirohito Kita - Rochester MN, US
David Sherris - Buffalo NY, US
Hirohito Kita - Rochester MN, US
Assignee:
The Research Foundation of State University of New York - Amherst NY
Mayo Foundation For Medical Education and Research - Rochester MN
Mayo Foundation For Medical Education and Research - Rochester MN
International Classification:
G01N 33/53, G01N 33/567, G01N 33/00, G01N 33/573, C12N 9/66
US Classification:
435 71, 435 72, 435 721, 435 724, 435 74, 435218
Abstract:
The present invention provides a method for identifying bacterial induced rhinosinusitis. The method comprises obtaining a nasal or paranasal mucus sample and detecting the presence of neutrophil degranulation in the mucus sample. Degranulation of neutrophils can be determined by morphological analysis of the cells in the mucus or by detection of released (i. e. , “free”) granule content markers such as neutrophil elastase or myeloperoxidase. Based on an accurate determination of the cause of sinusitis as described herein, an appropriate treatment can be instituted.