Inventors:
Jennifer Chow - Seattle WA, US
Ron Seubert - Sammamish WA, US
Arturo Ramirez - Seattle WA, US
Barry Friemel - Redmond WA, US
Jon Lundt - Seattle WA, US
Joshua Nordberg - Bainbridge Island WA, US
Assignee:
RareCyte, Inc. - Seattle WA
International Classification:
G01N 1/34
US Classification:
435 721, 436177, 422527, 436172, 436501
Abstract:
This disclosure is directed to systems and methods for immunomagnetic separation of a target analyte of a suspension from the other component materials of the suspension. The system may be composed of a tube, a magnetizable float, and a magnet. The magnetizable float is configured to propagate or introduce a magnetic field. In one aspect, the magnet is included in the magnetizable float. In another aspect, the magnet is external to the magnetizable float. The system may also include a solution containing a particle to conjugate with the target analyte to form a target analyte-particle complex. The particle is capable of being attracted by the magnetic field or magnetic gradient introduced by the magnet. The target analyte-particle complex may be attracted to the magnetizable float.