Inventors:
Kamel Khalili - Merion PA, US
Jennifer Gordon - Philadelphia PA, US
International Classification:
A61K 31/713, A61K 31/7105, C07H 21/02, C12N 15/85, C12N 15/86
US Classification:
514044000, 435320100, 536023100
Abstract:
RNA interference using small interfering RNAs which are specific for mRNA produced from the JCV agnoprotein and large T antigen genes inhibits expression of these and other primate polyomavirus genes. Primate polyomavirus infection, and diseases which are associated with primate polyomavirus infection, can be treated by administering the small interfering RNAs.