MRS. JENNIFER LAUREN HUNT, RD, LDN
Dietitian and Nutritionist at Health Park, Raleigh, NC

8231869, Jul 31, 2012

Oct 18, 2006

12/090782

Philip Scuderi, Jr. - Chapel Hill NC, US
Vikram Arora - Morrisville NC, US
Jennifer A. Hunt - Raleigh NC, US
Valery Novokhatny - Raleigh NC, US

Grifols Therapeutics Inc. - Research Triangle Park NC

A61K 38/48

424 9464

Methods of using polynucleotides and polypeptides relating to a recombinantly-modified plasmin(ogen) molecule are provided, including methods related to vitrectomy or vitreolysis. The plasmin(ogen) molecule has a single kringel domain N-terminal to the activation site present in the native human plasminogen molecule, and exhibits lysine-binding and significant enzymatic characteristics associated with the native enzyme.

8420079, Apr 16, 2013

Sep 1, 2011

13/223373

Jennifer Hunt - Raleigh NC, US
Valery Novokhatny - Raleigh NC, US

Grifols Therapeutics, Inc. - Research Triangle Park NC

A61K 38/48, C12N 9/50, A01N 43/04

424 9464, 435219

Polynucleotides and polypeptides relating to a recombinantly-modified plasmin(ogen) molecule are provided. The plasmin(ogen) molecule has a single kringle domain N-terminal to the activation site present in the native human plasminogen molecule, and exhibits lysine-binding and significant enzymatic characteristics associated with the native enzyme.

2014003, Jan 30, 2014

Mar 14, 2013

13/828374

- Barcelona, ES
THOMAS P. ZIMMERMAN - RALEIGH NC, US
JENNIFER A. HUNT - RALEIGH NC, US
CHARLES MILLER - APEX NC, US
SENTHIL RANGANATHAN - CARY NC, US
TONNY DESSOURCES - RALEIGH NC, US

C07K 14/47

530413, 530414, 530416

Described herein are methods for purifying recombinant, cell culture derived alpha-protease inhibitor and removing a colored species that co-purifies with the recA1PI protein. Also described are methods for reducing the iron in cell culture derived alpha-protease inhibitor.

2002013, Sep 26, 2002

Jul 30, 2001

09/918109

Paul Bernasconi - Chapel Hill NC, US
Ray Carpenter - Durham NC, US
Gary Powell - Morrisville NC, US
Robert Petrovich - Cary NC, US
Kimberly White - Durham NC, US
Jennifer Hunt - Raleigh NC, US

C12Q001/70, C12Q001/68, G01N033/53, C07K002/00, C07K004/00, C07K005/00, C07K007/00, C07K014/00, C07K016/00, C07K017/00, A61K038/00, C07K001/00

530/350000, 435/005000, 435/006000, 435/007100, 530/300000

A parallel high throughput method and kit for the discovery of small molecule interactors of target proteins, in particular, target proteins expressed from entire genomes or subsets thereof. The target module is prepared by binding selectively a target protein, modified to allow its detection, to a surrogate ligand that is linked to an individually detectable bead. Sets of target modules are mixed together in each chamber of a multi-chamber container. A test compound or collection of test compounds is added to each chamber, and the interaction of a compound with each target module is observed. A compound that is specific for a particular target protein will displace that protein from its target module. The identity of the target module so disrupted is determined by identifying the particular bead to which the displaced target protein was attached.

2012000, Jan 12, 2012

Mar 2, 2010

13/147491

Edward Koepf - Holly Springs NC, US
Myies Lindsay - Garner NC, US
Rebecca Silverstein - Cary NC, US
Jennifer Hunt - Raleigh NC, US
James Rebbeor - Garner NC, US
Thomas Zimmerman - Raleigh NC, US
Charles Miller - Apex NC, US
Anthony Caronna - Cary NC, US
Kenya Stokes - Cary NC, US

Talecris Biotherapeutics, Inc. - Research Triangle Park NC

C12N 9/68, C07K 14/435, C07K 1/18

435217, 530380

Compositions and methods for preparing plasminogen, in particular recombinant plasminogen, and compositions and methods of utilizing same for preparing plasmin are provided.