Inventors:
Anubhav Tripathi - Northboro MA, US
Leonard Mermel - Barrington RI, US
Aleksey Novikov - Providence RI, US
Leah Seward - North Attleboro MA, US
Jennifer Fieber - Tucson AZ, US
Assignee:
Brown University - Providence RI
International Classification:
C07H 21/04, G01N 21/64
Abstract:
This invention comprises a multiplex-capable oligonucleotide which is capable of hybridizing to at least one of the tcdB, tcdC, or cdtB genes, wherein, wherein said primer consists of a sequence selected from the group consisting of SEQ ID NOS: 1 through 9, or a sequence that exhibits no more than one substitution of a base to a sequence selected from the group consisting of SEQ ID NOS: 1 through 9 and method for polymerase chain reaction (PCR) determining of the presence of a toxigenic strain of in a biological sample utilizing said probes.