JENNIFER G CHE
Broker in Cambridge, MA
License number
Massachusetts 147843
Issued Date
Aug 31, 2009
Expiration Date
Nov 18, 2011
Type
Broker
Address
Address
Cambridge, MA 02139
Professional information
Jennifer G. Che, Cambridge MA - Lawyer
Office:
130 Waverly St, Cambridge, MA
ISLN:
920035113
Admitted:
2007
Antagonists Of Melanin Concentrating Hormone Receptor
US Patent:
2004010, Jun 3, 2004
Filed:
Jun 11, 2003
Appl. No.:
10/459682
Inventors:
Christopher Blackburn - Natick MA, US
Su-Jen Lai - Somerville MA, US
Jennifer Che - Cambridge MA, US
Martin Maguire - Woburn MA, US
Michael Patane - Andover MA, US
Matthew LaMarche - Reading MA, US
Courtney Cullis - Belmont MA, US
James Brown - Framingham MA, US
Anil Vasudevan - Gurnee IL, US
Jennifer Freeman - Grayslake IL, US
Mathew Mulhern - Hainesville IL, US
John Lynch - Kenosha WI, US
Ju Gao - Gurnee IL, US
Dariusz Wodka - Waukegan IL, US
Andrew Souers - Evanston IL, US
Rajesh Iyengar - Lindenhurst IL, US
Mary Verzal - Burlington WI, US
Philip Kym - Grayslake IL, US
Su-Jen Lai - Somerville MA, US
Jennifer Che - Cambridge MA, US
Martin Maguire - Woburn MA, US
Michael Patane - Andover MA, US
Matthew LaMarche - Reading MA, US
Courtney Cullis - Belmont MA, US
James Brown - Framingham MA, US
Anil Vasudevan - Gurnee IL, US
Jennifer Freeman - Grayslake IL, US
Mathew Mulhern - Hainesville IL, US
John Lynch - Kenosha WI, US
Ju Gao - Gurnee IL, US
Dariusz Wodka - Waukegan IL, US
Andrew Souers - Evanston IL, US
Rajesh Iyengar - Lindenhurst IL, US
Mary Verzal - Burlington WI, US
Philip Kym - Grayslake IL, US
Assignee:
Millennium Pharmaceuticals, Inc.
International Classification:
A61K031/4545, A61K031/452, C 07D 4 5/02, C 07D 4 1/02
US Classification:
514/317000, 514/318000, 514/326000, 546/194000, 546/207000
Abstract:
This invention provides compounds that are antagonists of melanin concentrating hormone receptor-1 (MCH-R1). The compounds are represented by formula I:
where m is zero or one, n is zero to two, Y is oxygen or —N(R)—, R, R, R, R, R, Rand Ring A are defined in the specification. Coumarin and quinolone compounds where Rand Rtogether form a fused benzo ring are preferred. The invention also provides compounds of formula VI where the coumarin moiety is replaced by a quinazolinone ring. The compounds are useful for treating MCH-R1-related disorders, particularly overweight conditions including obesity.
Jennifer Grace Che, Cambridge MA - Lawyer
Address:
130 Waverly St, Cambridge 02139
(617) 444-6525
(617) 444-6525
Licenses:
Massachusetts - Active 2007