JEFFREY M STEIN, MD
Osteopathic Medicine in New Haven, CT

6695857, Feb 24, 2004

Nov 5, 2002

10/288200

Lee R. Bolduc - Mountain View CA 94041
Jeffrey A. Stein - Woodbridge CT 06525
Paul C. DiCesare - Norwalk CT 06851
Peter F. Costa - Winthrop MA 02152
William A. Holmes - Marblehead MA 01945

A61B 1711

606153, 606155

A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel.

6451034, Sep 17, 2002

Sep 28, 2001

09/966118

Lee R. Bolduc - Mountain View CA 94041
Jeffrey A. Stein - Woodbridge CT 06525
Paul C. DiCesare - Norwalk CT 06851
Peter F. Costa - Winthrop MA 02152
William A. Holmes - Marblehead MA 01945

A61B 1711

606153, 606155

A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel.

6443965, Sep 3, 2002

Jan 8, 2001

09/756355

Lee R. Bolduc - Mountain View CA
Jeffrey A. Stein - Woodbridge CT
Paul C. DiCesare - Norwalk CT
Peter F. Costa - Winthrop MA
William A. Holmes - Marblehead MA

Heartport, Inc. - Redwood City CA

A61B 1711

606153, 606139, 606155, 606184, 606219

A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel.

6682541, Jan 27, 2004

Sep 16, 2002

10/244366

Lee R. Bolduc - Mountain View CA 94041
Jeffrey A. Stein - Woodbridge CT 06525
Paul C. DiCesare - Norwalk CT 06851
Peter F. Costa - Winthrop MA 02152
William A. Holmes - Marblehead MA 01945

A61B 1711

606153, 606155

A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel.

6676678, Jan 13, 2004

Sep 20, 2001

09/956708

Lee R. Bolduc - Mountain View CA
Jeffrey A. Stein - Woodbridge CT
Paul C. DiCesare - Norwalk CT
Peter F. Costa - Winthrop MA
William A. Holmes - Marblehead MA

Heartport, Inc. - Redwood City CA

A61B 1732

606184, 606153

A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel.

2005009, May 5, 2005

Nov 29, 2004

10/998795

Hanson Gifford - Woodside CA, US
Lee Bolduc - Mountain View CA, US
Jeffrey Stein - Woodbridge CT, US
Paul DiCesare - Norwalk CT, US
Peter Costa - Winthrop MA, US
William Holmes - Marblehead MA, US

A61B017/08

606153000

A system for performing an end-to-side vascular anastomosis including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis

8617190, Dec 31, 2013

Mar 28, 2011

13/073119

Lee R. Bolduc - Mountain View CA, US
Jeffrey A. Stein - Woodbridge CT, US
Paul C. DiCesare - Norwalk CT, US
Peter F. Costa - Winthrop MA, US
William A. Holmes - Marblehead MA, US

Heartport, Inc. - Redwood City CA

A61B 17/11

606153

A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel.

2005009, May 5, 2005

Nov 29, 2004

10/998779

Hanson Gifford - Woodside CA, US
Lee Bolduc - Mountain View CA, US
Jeffrey Stein - Woodbridge CT, US
Paul DiCesare - Norwalk CT, US
Peter Costa - Winthrop MA, US
William Holmes - Marblehead MA, US

A61B017/08

606153000

A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastonosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis

7112211, Sep 26, 2006

Jan 9, 2003

10/339434

Lee R. Bolduc - Mountain View CA, US
Jeffrey A. Stein - Woodbridge CT, US
Paul C. DiCesare - Norwalk CT, US
Peter F. Costa - Winthrop MA, US
William A. Holmes - Marblehead MA, US

Heartport, Inc. - Redwood City CA

A61B 17/11

606153, 606155

A system for performing an end-to-side vascular anastomosis. including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel.

2011009, Apr 21, 2011

Dec 23, 2010

12/977706

Roger E. Darois - Foster RI, US
Gus Felix - Cranston RI, US
Alan Bachman - Milford CT, US
Ray Adams - Ansonia CT, US
Joe Paul - Thomaston CT, US
Ed Chester - Norwalk CT, US
Adam Lehman - Northford CT, US
Barry Smith - Kenneth Square PA, US
Jeffrey A. Stein - Woodbridge CT, US

A61B 17/03

606151

A surgical fastener system includes a plurality of fasteners having a throughbore with an internally threaded portion. The fasteners may engage with a threaded mandrel that passes through the throughbore of the fasteners. A rotator may rotate the fasteners relative to the mandrel to move at least one of the fasteners along the mandrel, e.g., along the mandrel's longitudinal axis. A distal end of the mandrel may be inserted into a material, such as a tissue, prosthetic or other, and a fastener may be deployed from the distal end of the mandrel while the distal end is positioned in the material. The throughbore of the fasteners may include a threaded portion and an unthreaded portion, may include an angled face or other feature to aid in fastener deployment and/or have curved depressions in the head portion.