DR. JEFFREY LLOYD NOEBELS, MD
Ambulatory Health at Baylor Plz, Houston, TX

License number

Texas H2077

Professional information

Jeffrey Lloyd Noebels, Houston TX

Specialties:

Primary Care Doctor

Address:

1 Baylor Plz, Houston, TX 77030

Education:

Yale University, School of Medicine - Doctor of Medicine
Massachusetts General Hospital - Residency - Neurology

Board certifications:

American Board of Psychiatry and Neurology Certification in Neurology (Psychiatry and Neurology)

Dr. Jeffrey L Noebels - MD (Doctor of Medicine)

Hospitals:

1 Baylor Plz, Houston 77030
1 Baylor Plz, Houston 77030

Education:

Medical Schools
Yale University
Graduated: 1981

Dr At Baylor College Of Medicine

Location:

Houston, Texas Area

Industry:

Hospital & Health Care

Experience:

Baylor College of Medicine (Educational Institution; 5001-10,000 employees; Hospital & Health Care industry): Dr, (-)

In Vitro Method For Identifying A Clinical Disorder Associated With Nhe1 Mutation

US Patent:

5811244, Sep 22, 1998

Filed:

Sep 18, 1996

Appl. No.:

8/715142

Inventors:

Wayne N. Frankel - Bar Harbor ME
Gregory A. Cox - Bar Harbor ME
Cathleen M. Lutz - Bar Harbor ME
Jeffrey L. Noebels - Houston TX

Assignee:

The Jackson Laboratory - Bar Harbor ME
Baylor College of Medicine - Houston TX

International Classification:

G01N 3353

US Classification:

435 72

Abstract:

Disclosed is the identification of a mutation which is responsible for ataxia and epilepsy in a murine model system. More specifically, a mutation has been identified within the Nhe1 gene (also referred to as the Slc9a1 gene) which results in both ataxia and epilepsy. The specific mutation identified is an A to T transition at nucleotide 1639 which creates a premature stop codon. The identification of this mutation enables methods for the detection of clinical disorders associated with a defect in a cation exchanger (e. g. , Nhe1).