JEFFREY L CHEN, M.D.
Physical Therapy at Carmel Mountain Rd, San Diego, CA

6006747, Dec 28, 1999

Mar 20, 1997

8/821753

Robert Eisele - San Diego CA
Karen Davies - San Diego CA
Jeffrey Chen - San Diego CA
Bernard Greenspan - San Diego CA

Dura Pharmaceuticals, Inc. - San Diego CA

A61M 1500, A61M 1508

12820315

A dry powder inhaler has a lid pivotally attached to an inhaler housing. A medicine containing cartridge is attached to the top of the housing and includes a cartridge ring with apertures for holding dry powdered medicine. A slide-groove assembly located on the underside of the lid advances the cartridge ring to a next aperture when a user first opens, then closes the lid. A venturi air passageway assembly is contained within the housing of the dry powdered inhaler. The venturi air passageway assembly includes a tapered inlet section, a throat section, and a tapered outlet section. A pressure switch is advantageously located within the housing for actuating the mixing process within the mixing chamber. During inhalation, the pressure switch contained within the housing actuates the motor driven impeller within the mixing chamber of the inhaler when the pressure within the venturi air passageway reaches a predetermined level. The pressure at which the pressure switch closes corresponds to a specifically calibrated inhalation flow rate.

2006000, Jan 12, 2006

Sep 12, 2005

11/224406

Andrew Gieschen - San Diego CA, US
Michael Ligotke - San Diego CA, US
Jeffrey Chen - San Diego CA, US
Charles Ganem - San Diego CA, US
Bernard Greenspan - San Diego CA, US

A61M 15/00, A61M 16/00

128203150

A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater airflow and powder dispersion, without any increased effort by the patient.

7958890, Jun 14, 2011

Dec 4, 2008

12/328657

Andrew W. Gieschen - San Diego CA, US
Michael Ligotke - San Diego CA, US
Jeffrey Chen - San Diego CA, US
Charles F. Ganem - San Diego CA, US
Bernard Greenspan - San Diego CA, US

Quadrant Technologies Limited

A61M 15/00, A61M 16/00

12820315, 12820314, 12820319, 12820322, 12820323, 12820012

A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater airflow and powder dispersion, without any increased effort by the patient.

6971384, Dec 6, 2005

Feb 19, 2004

10/782449

Andrew W. Gieschen - San Diego CA, US
Michael Ligotke - San Diego CA, US
Jeffrey Chen - San Diego CA, US
Charles Ganem - San Diego CA, US
Bernard Greenspan - San Diego CA, US

Quadrant Technologies Limited - Nottingham

A61M015/00

12820315, 12820312, 604 58

A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater airflow and powder dispersion, without any increased effort by the patient.