Inventors:
Timothy J. Cunningham - Fort Washington PA, US
Lihua Yao - Wynnewood PA, US
Jeffrey I. Greenstein - Philadelphia PA, US
International Classification:
A61K 38/00, C07K 7/00, C12N 15/11, C12N 15/00, C12N 5/04, C12N 5/06, C12N 5/00, C12N 1/20, C12N 1/00, A01K 67/027, C07K 16/18, G01N 33/00, A61P 25/00
US Classification:
514 16, 530329, 536 231, 4353201, 435419, 435348, 435325, 4352523, 43525411, 800 13, 5303879, 436 86
Abstract:
The present invention relates to the discovery of a composition including a seven-amino acid peptide that promotes neuronal survival, inhibits inflammation, and is a potent inhibitor of sPL2A, and uses thereof.