Inventors:
Gerry R. Boss - La Jolla CA, US
Stephen B. Jones - San Diego CA, US
Jeffrey C. Chen - San Gabriel CA, US
Friederike von Lintig - San Diego CA, US
Stephanie Hoffman - Patatuma CA, US
Adam Kimmerly - San Diego CA, US
Joann Luu - San Jose CA, US
Matthew Christopher Mycroft - Sierra Madre CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
G01N 33/543
US Classification:
436518, 436524, 436527, 436528, 436532
Abstract:
The invention is a method for the isolation of molecules of interest using tubes in which at least a portion of the inner walls of the tube are coated with microbeads that are coated with a capture reagent to bind the molecule of interest. The microbeads may be glass or polymer beads. The invention is a method and apparatus for preparation of the tubes for use in the method of the invention. The invention is a method for determining ratios of guanine nucleotides bound to guanine-nucleotide binding proteins.