Inventors:
John D. Bradley - Brookline MA
Craig M. Thompson - Arlington MA
Jeffrey B. Moore - Chestnut Hill MA
C. Richard Wobbe - Lexington MA
Judith M. Healy - Lexington MA
Caroline E. Donnelly - Bedford MA
Assignee:
Scriptgen Pharmaceuticals, Inc. - Waltham MA
International Classification:
C12N 119, C12N 1531, C12N 1581, C12P 2100
Abstract:
The invention provides novel yeast cells comprising genes whose expression can be modulated by growth in the presence or absence of metal ions, methods for making such yeast cells, and methods of using such yeast cells for determining the requirement for expression of particular genes for the growth or viability of the yeast cells.