JEFFERY L. BLEICH, M.D.
Anesthesiologist Assistant at Pasteur Dr, Palo Alto, CA

2013017, Jul 4, 2013

Aug 17, 2012

13/589073

Jeffery Lee Bleich - Palo Alto CA, US
Paul David Mannheimer - Danville CA, US
Jeffrey Lawrence Michels - San Francisco CA, US
Marc David Anker - Palo Alto CA, US

Pulson, Inc. - Palo Alto CA

G09B 19/00

434247

Systems and methods are disclosed to enable a user to favorably coordinate the timing of musculoskeletal movement and skeletal muscle contraction and relaxation with the cardiac pumping cycle in order to improve perfusion of cardiac and peripheral skeletal muscle and other tissues, increase physiological efficiency, decrease myocardial stress, and enhance individual performance, health and safety during rhythmic physical activity. Additionally, systems and methods are disclosed to enable a user to avoid inadvertent unfavorable coordination of musculoskeletal movement and skeletal muscle contractions and relaxation cycles with the cardiac pumping cycle during physical activity.

8617163, Dec 31, 2013

May 20, 2011

13/112886

Jeffery L. Bleich - Palo Alto CA, US

Baxano Surgical, Inc. - Raleigh NC

A61B 17/00

606 79

Described herein are methods, systems and devices for cutting a ligament of a patient. In some embodiments, the method may include the steps of advancing a cannulated probe into a patient, advancing the distal end of the tissue modification device assembly posteriorly through the skin of the patient such that it exits the patient, exposing at least one tissue modification element of the tissue modification device assembly, and reciprocating at least a portion of the tissue modification device assembly by alternately pulling on proximal and distal portions of the tissue modification device assembly to draw the at least one tissue modification element across the ligament to cut the ligament, in some embodiments, the system may include a probe, a tissue modification device, and a sheath. The tissue modification device may include a proximal handle, at least one tissue modification element configured cut ligament, and a sharp distal tip.

8398641, Mar 19, 2013

Dec 27, 2011

13/338103

Michael P. Wallace - Pleasanton CA, US
Robert Garabedian - Sunnyvale CA, US
Nestor C. Cantorna - Union City CA, US
Jeffery L. Bleich - Palo Alto CA, US
Roy Leguidleguid - Union City CA, US
Ronald Leguidleguid - Union City CA, US

Baxano, Inc. - San Jose CA

A61B 17/00

606 79

Described herein are devices and methods for cutting tissue in a patient. In some embodiments, a bimanually controlled device may include a tissue modification region; at least two flexible elongate lengths of cable that extend substantially adjacent to each other proximally to distally; a plurality of rungs extending between the lengths of cable; and a pair of flexible elongate cutting members extending along the length of the tissue modification region of the device. Each elongate cutting member has a thickness cuts a discrete trough into tissue to a depth that is greater than the thickness of the cutting member. The device may further include a substrate sized and configured to releasably hold the cutting members a distance from one another and a pair of couplers positioned toward an outer edge region of the substrate and configured to releasably secure a cutting member to the outer edge region of the substrate.

2008010, May 1, 2008

Oct 10, 2007

11/870370

Gregory SCHMITZ - Los Gatos CA, US
Jeffery Bleich - Palo Alto CA, US
Eric Miller - Los Gatos CA, US
Scott Smith - Redwood Shores CA, US

A61B 17/32, A61B 18/14, A61N 1/36

606079000, 606045000, 607117000

A method for percutaneously removing ligamentum flavum tissue in a spine to treat spinal stenosis may involve percutaneously advancing a distal portion of a tissue removal cannula into the ligamentum flavum tissue, uncovering a side-opening aperture disposed on the distal portion of the cannula to expose a tissue cutter disposed in the cannula, and cutting ligamentum flavum tissue using the tissue cutter while the aperture is uncovered. A device for percutaneously removing ligamentum flavum tissue in a spine to treat spinal stenosis may include a cannula including a side-facing aperture, an aperture cover slidably coupled with the cannula and configured to advance and retract to cover and uncover the aperture, and a tissue cutter slidably disposed within the cannula and configured to extend through the aperture to cut ligamentum flavum tissue.

2011006, Mar 10, 2011

Oct 25, 2010

12/911537

Michael P. Wallace - Pleasanton CA, US
Robert Garabedian - Sunnyvale CA, US
Gregory B. Arcenio - Redwood City CA, US
Jeffery L. Bleich - Palo Alto CA, US
Vahid Saadat - Saratoga CA, US
Winnie Chung - San Jose CA, US

A61M 25/00, A61B 17/16

604528, 606 79

Described herein are devices, systems and methods for treating target tissue in a patient's spine. In general, the methods include the steps of advancing a wire into the patient from a first location, through a neural foramen, and out of the patient from a second location; connecting a tissue modification device to the wire; positioning the tissue modification device through the neural foramen using the wire; modifying target tissue in the spine by moving the tissue modification device against the target tissue; and delivering an agent to modified target tissue, wherein the agent is configured to inhibit blood flow from the modified target tissue. In some embodiments, the step of modifying target tissue comprises removing target tissue located ventral to the superior articular process while avoiding non-target tissue located lateral to the superior articular process.

7963915, Jun 21, 2011

Oct 15, 2005

11/251186

Jeffery L. Bleich - Palo Alto CA, US

Baxano, Inc. - San Jose CA

A61B 17/00, A61B 17/88, A61B 1/00

600184, 606 79, 606 82, 606 86 R, 606279

Methods and apparatus are provided for selective surgical removal of tissue. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. The sharp tip of the needle in the epidural space, can be converted to a blunt tipped instrument for further safe advancement. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. A nerve stimulator may be provided to reduce a risk of inadvertent neural abrasion.

7578819, Aug 25, 2009

Jul 13, 2006

11/457416

Jeffery L. Bleich - Palo Alto CA, US
Ron Leguidleguid - Fremont CA, US
Jefferey Bleam - Boulder Creek CA, US

Baxano, Inc. - Mountain View CA

A61B 5/05, A61B 5/04, A61B 17/00, A61B 18/04, A61B 17/56, A61B 17/20, A61N 1/00

606 53, 607 48, 607115, 607116, 607117, 606 1, 606 32, 600554, 604 22

A method in which a probe is advanced between a neural tissue structure and a non-neural tissue structure such as the intervertebral foramen. The probe includes electrodes on opposite surfaces. Threshold currents required to stimulate action potentials for each electrode are determined. A ratio of the threshold currents are calculated. Tissue is removed from the non-neural tissue structure when the ratio is greater than a predetermined threshold.

8409206, Apr 2, 2013

May 4, 2010

12/773595

Michael P. Wallace - Pleasanton CA, US
Robert Garabedian - Mountain View CA, US
Nestor C. Cantorna - Fremont CA, US
Jeffery L. Bleich - Palo Alto CA, US
Roy Leguidleguid - Union City CA, US
Ronald Leguidleguid - Fremont CA, US

Baxano, Inc. - San Jose CA

A61B 17/00

606 79

Described herein are devices, systems and methods for cutting tissue in a patient. In some embodiments, a tissue modification region of a device includes a pair of flexible elongate cutting members extending along the length of the tissue modification region. Each elongate cutting member may be configured to cut a discrete trough into tissue to a depth that is greater than the thickness of the cutting member. In some embodiments, the device includes a spacer. The spacer may be sized and configured to operate in one of two modes. A first mode, in which the spacer is coupled to the cutting members such that it holds a portion of each of the two cutting members a distance from one another, and a second mode, in which at least a portion of the spacer is moved away from a cutting member to allow the cutting members to cut further into tissue.

2008016, Jul 3, 2008

Oct 3, 2006

11/538345

Gregory Schmitz - Los Gatos CA, US
Jeffery L. Bleich - Palo Alto CA, US
Eric C. Miller - Los Gatos CA, US

BAXANO, INC. - Mountain View CA

A61B 17/00

606 79

A device for cutting ligament and/or bone tissue in a lateral recess and/or an intervertebral foramen of a spine of a patient to treat spinal stenosis may include: an elongate shaft having a rigid proximal portion and a distal portion articulatable relative to the proximal portion; a handle coupled with the proximal portion of the shaft; a tissue cutter disposed on one side of the distal portion of the shaft; a first actuator coupling the handle with the tissue cutter for activating the tissue cutter to cut tissue; and a second actuator coupling the handle with the distal portion for articulating the distal portion relative to the proximal portion. In some embodiments, the distal portion of the shaft may be configured to pass at least partway into an intervertebral foramen of the patient's spine.