JEAN M MUKHERJEE
Veterinary in Worcester, MA
License number
Massachusetts 4908
Issued Date
May 27, 1999
Expiration Date
Feb 28, 2017
Type
Veterinarian
Address
Address
Worcester, MA 01606
Professional information
Methods And Systems For Multi-Antibody Therapies
US Patent:
2011012, Jun 2, 2011
Filed:
Sep 24, 2010
Appl. No.:
12/889511
Inventors:
Charles B. Shoemaker - North Grafton MA, US
Jean Mukherjee - Worcester MA, US
Jean Mukherjee - Worcester MA, US
International Classification:
A61K 39/395, A61P 31/12, A61P 31/04, A61P 33/00, A61P 35/00, A61P 39/02, C07K 14/00, C07H 21/04, C12N 15/63, C12N 5/10, A61K 38/02, C12N 1/00
US Classification:
4241391, 4241301, 530350, 536 231, 4353201, 435325, 514 11, 435410, 435243
Abstract:
The present invention relates to methods and systems for administering antibody therapeutic agents. The methods include administering one or more (e.g., two or three) binding agents, wherein each of the binding agents has one or more monomers that have a binding region that is specific to a portion of a disease agent and one or more copies of a tag. The binding agents can be specific to one or more portions of the same or different disease agents. The tag is the same for each of the binding agents. The methods include administering an anti-tag antibody, wherein the anti-tag antibody has an anti-tag region that is specific to the tag, and can have an immunoglobulin (e.g., IgA, IgD, IgE, IgG, and IgM.). Disease agents include bacteria, bacterial proteins, viruses, viral proteins, cancer cells, and proteins or toxins produced therefrom or from other sources such as snakes, insects, plants, etc. In particular, the present invention includes methods and systems for binding agents having one or more monomers that are specific to neurotoxins that cause botulism.
Methods And Systems For Multi-Antibody Therapies
US Patent:
2010027, Nov 4, 2010
Filed:
Feb 18, 2008
Appl. No.:
12/032744
Inventors:
Charles B. Shoemaker - North Grafton MA, US
Jorge A. Sepulveda Toepfer - Shrewbury MA, US
Jean Mukherjee - Worcester MA, US
Jorge A. Sepulveda Toepfer - Shrewbury MA, US
Jean Mukherjee - Worcester MA, US
International Classification:
A61K 39/395, A61K 39/40, C12N 5/10, C12N 15/63, A61K 38/16, C07K 14/00, A61P 33/00, A61P 35/04, A61P 31/04, A61P 31/12, A61P 31/10
US Classification:
4241391, 4241301, 4241641, 435325, 4353201, 514 212, 530350, 536 231
Abstract:
The present invention relates to methods and systems for administering antibody therapeutic agents. The methods include administering one or more (e.g., two or three) binding agents, wherein each of the binding agents has a binding region that is specific to a portion of a disease agent and one or more copies of a tag. The binding agents can be specific to one or more portions of the same or different disease agents. The tag is the same for each of the binding agents. The methods include administering an anti-tag antibody, wherein the anti-tag antibody has an anti-tag region that is specific to the tag, and can have an immunoglobulin (e.g., IgA, IgD, IgE, IgG, and IgM.). Disease agents include bacterial proteins, viral proteins, cancer cells, and proteins or toxins produced therefrom. In particular, the present invention includes methods and systems for binding agents that are specific to neurotoxins that cause botulism.