JAY SNOW TEICH
Pilots at Sawyerhill Rd, Berlin, MA
License number
Massachusetts C1050796
Issued Date
Jun 2016
Expiration Date
Jun 2018
Category
Airmen
Address
Address
220 Sawyerhill Rd, Berlin, MA 01503
Professional information
Method And Device For Measuring Multiple Physiological Properties Of Cells
US Patent:
2010022, Sep 9, 2010
Filed:
May 19, 2010
Appl. No.:
12/782806
Inventors:
Jay S. Teich - Berlin MA, US
Andy C. Neilson - Groton MA, US
Michael R. Sweeney - Pelham NH, US
Geoff Uhl - Littleton CO, US
Andy C. Neilson - Groton MA, US
Michael R. Sweeney - Pelham NH, US
Geoff Uhl - Littleton CO, US
International Classification:
C12M 1/34
US Classification:
4352884, 4352871, 4352887
Abstract:
A method of analyzing cells disposed in media within a vessel includes the steps of providing a vessel having an original volume of media about the cells, reducing the original volume of media about at least a portion of the cells to define a reduced volume of media, and analyzing a constituent related to the cells within the reduced volume of media. An apparatus for analyzing cells includes a stage adapted to receive a vessel holding cells and a volume of media, a plunger adapted to receive a barrier to create a reduced volume of media within the vessel including at least a portion of the cells, the barrier adapted for insertion into the vessel by relative movement of the stage and the plunger, and a sensor in sensing communication with the reduced volume of media, wherein the sensor is configured to analyze a constituent disposed within the reduced volume.
Analysis Of Metabolic Activity In Cells Using Extracellular Flux Rate Measurements
US Patent:
2007008, Apr 19, 2007
Filed:
Oct 10, 2006
Appl. No.:
11/545714
Inventors:
Andy Neilson - Groton MA, US
Jay Teich - Berlin MA, US
Min Wu - Carlisle MA, US
David Ferrick - Carlisle MA, US
Jay Teich - Berlin MA, US
Min Wu - Carlisle MA, US
David Ferrick - Carlisle MA, US
International Classification:
C12Q 1/02
US Classification:
435029000
Abstract:
Disclosed are methods for non-destructively measuring in vitro the effect on cellular metabolism of the addition to animal cells in culture of a soluble molecule potentially capable of perturbing the biological state of the cells, such as a drug or drug candidate, a toxin, a ligand known or suspected to bind to a cell surface receptor, a nutrient, a cytokine, a growth factor, a chemokine, a metabolism inhibitor or stimulator. Also disclosed are methods for measuring cell viability, vitality, or quality, e.g., in anticipation of the execution of an experiment on the cells. The measurements are done by observing alteration in the rates of consumption or production of extracellular solutes related to aerobic and anaerobic cellular metabolism, such as oxygen, protons, nutrients, carbon dioxide, lactate, or lactic acid. The methods are particularly useful in drug discovery efforts, such as cancer drug discovery and searches for modulators of cellular metabolism.
Method And Device For Measuring Multiple Physiological Properties Of Cells
US Patent:
7851201, Dec 14, 2010
Filed:
Nov 9, 2009
Appl. No.:
12/614773
Inventors:
Jay S. Teich - Berlin MA, US
Andy C. Neilson - Groton MA, US
Michael R. Sweeney - Pelham NH, US
Geoff Uhl - Littleton CO, US
Andy C. Neilson - Groton MA, US
Michael R. Sweeney - Pelham NH, US
Geoff Uhl - Littleton CO, US
Assignee:
Seahorse Bioscience, Inc. - Billerica MA
International Classification:
C12M 1/34
US Classification:
4352871
Abstract:
A method of analyzing cells disposed in media within a vessel includes the steps of providing a vessel having an original volume of media about the cells, reducing the original volume of media about at least a portion of the cells to define a reduced volume of media, and analyzing a constituent related to the cells within the reduced volume of media. An apparatus for analyzing cells includes a stage adapted to receive a vessel holding cells and a volume of media, a plunger adapted to receive a barrier to create a reduced volume of media within the vessel including at least a portion of the cells, the barrier adapted for insertion into the vessel by relative movement of the stage and the plunger, and a sensor in sensing communication with the reduced volume of media, wherein the sensor is configured to analyze a constituent disposed within the reduced volume.