DR. JAY L ZWEIER, MD
Osteopathic Medicine at Colts Neck Rd, Blacklick, OH
License number
Ohio 35082487
Category
Osteopathic Medicine
Type
Cardiovascular Disease
License number
Ohio D0026969
Category
Osteopathic Medicine
Type
Cardiovascular Disease
Address
Address
2858 Colts Neck Rd, Blacklick, OH 43004
Phone
(614) 855-5071
(614) 746-9696
(614) 746-9696
Professional information
Dr. Jay L Zweier, Blacklick OH - MD (Doctor of Medicine)
Specialties:
Cardiology
Address:
2858 Colts Neck Rd, Blacklick 43004
(614) 855-5071 (Phone)
(614) 855-5071 (Phone)
Languages:
English
Education:
Medical School
University of Maryland At Baltimore / Professional Schools
Graduated: 1981
University of Maryland At Baltimore / Professional Schools
Graduated: 1981
Nanoparticulate Probe For In Vivo Monitoring Of Tissue Oxygenation
US Patent:
8568694, Oct 29, 2013
Filed:
Jan 15, 2010
Appl. No.:
12/688767
Inventors:
Periannan Kuppusamy - New Albany OH, US
Ramasamy P. Pandian - Columbus OH, US
Narasimham L. Parinandi - Upper Arlington OH, US
Jay L. Zweier - Blacklick OH, US
Ramasamy P. Pandian - Columbus OH, US
Narasimham L. Parinandi - Upper Arlington OH, US
Jay L. Zweier - Blacklick OH, US
Assignee:
The Ohio State University Research Foundation - Columbus OH
International Classification:
A61B 5/055, C07B 47/00, C07D 487/22
US Classification:
424 93, 424 961, 540145
Abstract:
A new class of micro- and nano-particulate paramagnetic spin probes especially useful for magnetic resonance imaging techniques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI). The probes are lithium phthalocyanine derivative compounds. Also provided are suspensions and emulsions comprising lithium phthalocyanine derivative probes. Also provided are noninvasive methods for measuring noninvasive methods of measuring oxygen concentration, oxygen partial pressure, oxygen metabolism, and nitric oxide concentration in a specific tissue, organ, or cell in vivo or in vitro.
Methods For In Vivo Atherosclerotic Plaque Characterization Using Magnetic Susceptibility To Identify Symptom-Producing Plaques
US Patent:
2010028, Nov 11, 2010
Filed:
Jan 2, 2009
Appl. No.:
12/811292
Inventors:
Subha V. Raman - Columbus OH, US
Orlando P. Simonetti - Columbus OH, US
Jay L. Zweier - Blacklick OH, US
Orlando P. Simonetti - Columbus OH, US
Jay L. Zweier - Blacklick OH, US
Assignee:
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION - Columbus OH
International Classification:
A61K 49/06, A61K 49/00, A61B 5/055, G06K 9/00
US Classification:
424 93, 424 91, 600411, 382131
Abstract:
Methods and uses of in vivo atherosclerotic plaque characterization in a subject in need thereof, that include detecting a level of one or more iron complexes in plaque in the subject, and comparing detected level to a known value determined from subjects without an atherosclerotic condition are disclosed.
Nanoparticulate Probe For In Vivo Monitoring Of Tissue Oxygenation
US Patent:
7662362, Feb 16, 2010
Filed:
Sep 7, 2004
Appl. No.:
10/935297
Inventors:
Periannan Kuppusamy - New Albany OH, US
Ramasamy P. Pandian - Columbus OH, US
Narasimham L. Parinandi - Upper Arlington OH, US
Jay L. Zweier - Blacklick OH, US
Ramasamy P. Pandian - Columbus OH, US
Narasimham L. Parinandi - Upper Arlington OH, US
Jay L. Zweier - Blacklick OH, US
Assignee:
The Ohio State University Research Foundation - Columbus OH
International Classification:
A61B 5/055, C07B 47/00, C07D 487/22
US Classification:
424 93, 540145
Abstract:
A new class of micro- and nano-particulate paramagnetic spin probes especially useful for magnetic resonance imaging techniques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI). The probes are lithium phthalocyanine derivative compounds. Also provided are suspensions and emulsions comprising lithium phthalocyanine derivative probes. Also provided are noninvasive methods for measuring noninvasive methods of measuring oxygen concentration, oxygen partial pressure, oxygen metabolism, and nitric oxide concentration in a specific tissue, organ, or cell in vivo or in vitro.
Ampo Spin Traps
US Patent:
2006027, Dec 7, 2006
Filed:
Nov 23, 2005
Appl. No.:
11/286682
Inventors:
Frederick Villamena - Columbus OH, US
Christopher Hadad - Dublin OH, US
Jay Zweier - Blacklick OH, US
Christopher Hadad - Dublin OH, US
Jay Zweier - Blacklick OH, US
International Classification:
A61K 31/4015, G01N 37/00, C07D 207/24
US Classification:
514423000, 548537000, 436056000
Abstract:
Provided are spin traps for the study of radical formation in vivo or in vitro. 5-carbamoyl-5-methyl-1-pyrroline N-oxide (AMPO) and 2-amino-5-carbamoyl-5-methyl-1-pyrroline N-oxide (NH-AMPO), have the following structures, respectively:
as well as salts thereof.