JAY J LEVY
Real Estate Commission in Paoli, PA
License number
Pennsylvania RS214080L
Category
Real Estate Commission
Type
Real Estate Salesperson-Standard
Address
Address
Paoli, PA 19301
Professional information
Parathyroid Hormone Antagonists With Simplified Synthetic Methodology
US Patent:
4771124, Sep 13, 1988
Filed:
May 26, 1987
Appl. No.:
7/054359
Inventors:
Michael Rosenblatt - Ardmore PA
Lynn H. Caporale - Lansdale PA
Ruth F. Nutt - Green Lane PA
Jay J. Levy - Paoli PA
Michael Chorev - Jerusalem, IL
Lynn H. Caporale - Lansdale PA
Ruth F. Nutt - Green Lane PA
Jay J. Levy - Paoli PA
Michael Chorev - Jerusalem, IL
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07K 710
US Classification:
530324
Abstract:
The present invention relates to the use of peptide hormone analogues as inhibitors of their respective naturally occurring peptide hormone and methods of synthesis of such analogues. The structure of the peptide hormone analogues is exemplified by parathyroid hormone wherein Trp. sup. 23 is substituted by L-Phe or other hydrophobic amino acids such as Leu, Nle, Val, Tyr, beta-napthylalanine and alpha-napthylalanine.