JAY CHUNG
Osteopathic Medicine at Marbury Rd, Bethesda, MD
License number
Maryland D0040385
Category
Osteopathic Medicine
Type
Endocrinology, Diabetes & Metabolism
Address
Address
7606 Marbury Rd, Bethesda, MD 20817
Phone
(301) 339-3135
Personal information
See more information about JAY CHUNG at radaris.comName
Address
Phone
104 Fallsgrove Blvd APT 3301, Rockville, MD 20850
6143 Good Hunters Ride, Columbia, MD 21045
7606 Marbury Rd, Bethesda, MD 20817
8034 Andiron Ln, Jessup, MD 20794
10 Brent Ct, Rockville, MD 20854
Professional information
Dr. Jay H Chung, Bethesda MD - MD (Doctor of Medicine)
Specialties:
Internal Medicine
Address:
JOHN JANIK MD
10 Ctr Dr SUITE 10, Bethesda 20892
(301) 402-2913 (Phone), (301) 402-1001 (Fax)
10 Ctr Dr SUITE 10, Bethesda 20892
(301) 402-2913 (Phone), (301) 402-1001 (Fax)
Certifications:
Internal Medicine, 1991
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Harvard Medical School
Graduated: 1988
Brigham and Womens Hospital
National Institutes Of Health Clinical Center
Harvard Medical School
Graduated: 1988
Brigham and Womens Hospital
National Institutes Of Health Clinical Center
Methods For Detecting Intermolecular Interactions In Vivo And In Vitro
US Patent:
6444421, Sep 3, 2002
Filed:
Apr 2, 1998
Appl. No.:
09/054281
Inventors:
Jay H. Chung - Bethesda MD
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
C12Q 168
US Classification:
435 6, 435 691, 435 911, 435 913, 435 914, 435455
Abstract:
Methods for assessing intermolecular interactions in vivo and in vitro are provided. Methods are provided for detecting protein-DNA interactions in vivo, in which a cell having a chimeric guide endonuclease molecule and a target nucleic acid is provided, and cleavage of the target nucleic acid by the chimeric guide endonuclease molecule is monitored. Cleavage by the chimeric guide molecule corresponds to binding of the guide domain to the target nucleic acid, or to a protein associated with the nucleic acid. The methods of the invention are adapted to cleavage of target nucleic acids, amplification of target nucleic acids, detection of target nucleic acids, screening of genomic target nucleic acid sequences for guide binding domains, and screening for modulators of chimeric guide binding domain activity. Also provided are methods for detecting interactions between other molecules, including hormones and receptors, enzymes and substrates, and the like.
Methods For Detecting Intermolecular Interactions In Vivo And In Vitro
US Patent:
2003006, Apr 3, 2003
Filed:
Jul 8, 2002
Appl. No.:
10/191949
Inventors:
Jay Chung - Bethesda MD, US
Assignee:
The Government of the U.S.A. as represented by the Secretery of the Dept. of Health & Human Services - Rockville MD
International Classification:
C12Q001/68, C12P019/34, C12N015/85
US Classification:
435/006000, 435/091200, 435/455000
Abstract:
Methods for assessing intermolecular interactions in vivo and in vitro are provided. Methods are provided for detecting protein-DNA interactions in vivo, in which a cell having a chimeric guide endonuclease molecule and a target nucleic acid is provided, and cleavage of the target nucleic acid by the chimeric guide endonuclease molecule is monitored. Cleavage by the chimeric guide molecule corresponds to binding of the guide domain to the target nucleic acid, or to a protein associated with the nucleic acid. The methods of the invention are adapted to cleavage of target nucleic acids, amplification of target nucleic acids, detection of target nucleic acids, screening of genomic target nucleic acid sequences for guide binding domains, and screening for modulators of chimeric guide binding domain activity. Also provided are methods for detecting interactions between other molecules, including hormones and receptors, enzymes and substrates, and the like.
Dna Sequence Which Acts As A Chromatin Insulator Element To Protect Expressed Genes From Cis-Acting Regulatory Sequences In Mammalian Cells
US Patent:
5610053, Mar 11, 1997
Filed:
Jul 29, 1994
Appl. No.:
8/283125
Inventors:
Jay H. Chung - Bethesda MD
Gary Felsenfeld - Chevy Chase MD
Gary Felsenfeld - Chevy Chase MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
and Human Services - Washington DC
International Classification:
C07H 2104, C12N 510, C12N 1511, C12P 2100
US Classification:
4351723
Abstract:
A newly-characterized chromatin insulator element isolated from the DNA of a higher eukaryotic organism and contained in vector constructs is described. The insulator element of the invention comprises a DNA sequence which contains a 5' constitutive hypersensitive site whose functional activity and biochemical characterization as a pure insulator were previously unknown. A core DNA sequence having strong insulator activity is described. The insulator element, including the core sequence, have been demonstrated for the first time in mammalian cells to function to buffer or insulate an expressed gene from the activity of cis-acting regulatory elements, such as enhancers, in the surrounding chromatin or DNA.
Dna-Pkcs Modulates Energy Regulation And Brain Function
US Patent:
2010013, May 27, 2010
Filed:
Jul 3, 2008
Appl. No.:
12/667840
Inventors:
Jay Hang Chung - Bethesda MD, US
Myung Kyung Kim - Bethesda MD, US
Sung Jun Park - Potomac MD, US
Myung Kyung Kim - Bethesda MD, US
Sung Jun Park - Potomac MD, US
Assignee:
The United State of America, as represented by the Secretary of the Dept of Health and Human Service - Rockville MD
International Classification:
A61K 31/7088, A61K 31/535, A61K 31/5377, A61K 31/5513
US Classification:
514 44 R, 5142312, 5142335, 5142358, 514218
Abstract:
The invention relates to new functions of the DNA-PKcs gene product in energy metabolism, brain function and physical fitness.
Modulating Response To Genotoxic Stress
US Patent:
2005005, Mar 17, 2005
Filed:
Aug 10, 2004
Appl. No.:
10/916083
Inventors:
Jay Chung - Bethesda MD, US
International Classification:
C12Q001/68, C12N015/85
US Classification:
514012000, 435455000
Abstract:
Methods are disclosed to modify cellular sensitivity to genotoxic stress by introducing into a cell a biological macromolecule that alters phosphorylation of BRCA1 by Cds1. Such biological macromolecules may be used to enhance genotoxin-induced cell death, or alter genotoxin-induced gene expression. Alternatively, such biological macromolecules may be used to enhance cell survival following exposure to genotoxic agents. Methods are also disclosed for determining exposure to genotoxic stress by assessing the phosphorylation status of BRCA1, for example by using antibody molecules disclosed herein.
Modulating Response To Genotoxic Stress
US Patent:
2002010, Aug 1, 2002
Filed:
Sep 5, 2001
Appl. No.:
09/947258
Inventors:
Jay Chung - Bethesda MD, US
Assignee:
The Government of the United States of America
International Classification:
A61K048/00, A61K038/51
US Classification:
424/094500, 514/044000
Abstract:
Methods are disclosed to modify cellular sensitivity to genotoxic stress by introducing into a cell a biological macromolecule that alters phosphorylation of BRCA1 by Cds1. Such biological macromolecules may be used to enhance genotoxin-induced cell death, or alter genotoxin-induced gene expression. Alternatively, such biological macromolecules may be used to enhance cell survival following exposure to genotoxic agents. Methods are also disclosed for determining exposure to genotoxic stress by assessing the phosphorylation status of BRCA1, for example by using antibody molecules disclosed herein.
Effect Of Bst2 On Inflammation
US Patent:
2008029, Dec 4, 2008
Filed:
Jun 1, 2007
Appl. No.:
11/757329
Inventors:
Myung Kim - Bethesda MD, US
Jay Chung - Bethesda MD, US
June-Young Park - Seoul, KR
Hyouna Yoo - Seoul, KR
Sang-Min Lee - Kyeonggi-do, KR
Yoon-Seok Lee - Kyunggi-do, KR
Mison Koo - Seoul, KR
Sang-Ho Park - Kyeonggi-do, KR
Juheng Lee - Seoul, KR
Young Mi Hur - Seoul, KR
Jay Chung - Bethesda MD, US
June-Young Park - Seoul, KR
Hyouna Yoo - Seoul, KR
Sang-Min Lee - Kyeonggi-do, KR
Yoon-Seok Lee - Kyunggi-do, KR
Mison Koo - Seoul, KR
Sang-Ho Park - Kyeonggi-do, KR
Juheng Lee - Seoul, KR
Young Mi Hur - Seoul, KR
International Classification:
A61K 39/395, A61K 39/00, C07K 16/18, G01N 33/53, A01K 67/027, A61P 29/00, C12P 21/00
US Classification:
4241411, 4241841, 5303873, 5303881, 435 71, 800 18, 435 691
Abstract:
The application disclose a method of preventing immune cells from binding to other cells, which includes contacting the immune cells and the other cells with a composition comprising Bst2 antagonist.
Treatment Of Inflammation Using Bst2 Inhibitor
US Patent:
8329186, Dec 11, 2012
Filed:
Nov 2, 2009
Appl. No.:
12/611090
Inventors:
Myung Kim - Bethesda MD, US
Jay Chung - Bethesda MD, US
June-Young Park - Seoul, KR
Hyouna Yoo - Kyunggi, KR
Sang-Min Lee - Kyunggi-do, KR
Yoon-Seok Lee - Kyunggi-do, KR
Mison Koo - Seoul, KR
Sang-Ho Park - Kyunggi-do, KR
Jay Chung - Bethesda MD, US
June-Young Park - Seoul, KR
Hyouna Yoo - Kyunggi, KR
Sang-Min Lee - Kyunggi-do, KR
Yoon-Seok Lee - Kyunggi-do, KR
Mison Koo - Seoul, KR
Sang-Ho Park - Kyunggi-do, KR
Assignee:
Isu Abxis Co., Ltd - Seoul
International Classification:
A61K 39/00, A61K 38/00
US Classification:
4241841, 4241851
Abstract:
The application discloses a method of preventing immune cells from binding to other cells, which includes contacting the immune cells and the other cells with a composition comprising Bst2 antagonist.
Effect Of Bst2 On Inflammation
US Patent:
7740856, Jun 22, 2010
Filed:
Jun 20, 2006
Appl. No.:
11/471853
Inventors:
Myung Kim - Bethesda MD, US
Jay Chung - Bethesda MD, US
June-Young Park - Seoul, KR
Hyouna Yoo - Seoul, KR
Sang-Min Lee - Kyeonggi-do, KR
Yoon-Seok Lee - Kyeonggi-do, KR
Mison Koo - Seoul, KR
Sang-Ho Park - Kyeonggi-do, KR
Jay Chung - Bethesda MD, US
June-Young Park - Seoul, KR
Hyouna Yoo - Seoul, KR
Sang-Min Lee - Kyeonggi-do, KR
Yoon-Seok Lee - Kyeonggi-do, KR
Mison Koo - Seoul, KR
Sang-Ho Park - Kyeonggi-do, KR
Assignee:
ISU Abxis Co., Ltd. - Seoul
International Classification:
A61K 39/00, A61K 38/00
US Classification:
4241841, 4241851, 514 2
Abstract:
The application disclose a method of preventing immune cells from binding to other cells, which includes contacting the immune cells and the other cells with a composition comprising Bst antagonist.