JAY A STEIN
Broker in Framingham, MA

5755228, May 26, 1998

Sep 26, 1995

8/534131

Kevin E. Wilson - Cambridge MA
Donald Barry - Norwood MA
Dennis G. Lamser - Arlington MA
John P. O'Brien - Brookline MA
Jay A. Stein - Framingham MA

Hologic, Inc. - Waltham MA

A61B 800

12866006

An improvement to calibration and quality assurance of an ultrasonic bone analysis apparatus is achieved by using phantoms. A received ultrasound signal that passed through a first phantom is used as a baseline for calculating BUA. The first phantom has an attenuation-versus-frequency profile that is substantially flat in a frequency range of 200 to 1000 kHz and a sound impedance that approximates that of soft human tissue. A propagation time of the signal is used to calibrate a zero point of the apparatus. A second phantom has an attenuation in a frequency range of 200-1000 kHz which approximates that of a human foot, including an attenuation-versus-frequency profile that is substantially linear in the frequency range of 200-600 kHz and is approximately 1 dB/MHz per mm. A received ultrasound signal that passed through the second phantom is used to calibrate the apparatus for a BUA calculation, and can also be used for at least one of determining and correcting a drift of the apparatus. A third phantom has a predetermined SOS that is substantially independent of temperature.

5838765, Nov 17, 1998

Jun 7, 1995

8/486368

Russell J. Gershman - Middleborough MA
Richard E. Cabral - Tewksbury MA
Noah Berger - Waltham MA
Jay A. Stein - Framingham MA

Hologic, Inc. - Waltham MA

G21K 510

378196

A whole body x-ray bone densitometry system includes a table extending parallel to a Y-axis of an XYZ coordinate system for supporting a patient at a patient position; an x-ray source for emitting a narrow angle fan beam of x-rays to irradiate at any one time a scan line which is transverse to the Y-axis and is substantially shorter than the width of a body cross-section of a typical adult patient occupying the patient position. An x-ray detector is aligned with the source along a source-detector axis which is transverse to the Y-axis, for receiving x-rays from the source within the angle of the fan beam after passage thereof through the patient position. The detector has a number of detecting elements arranged along a direction transverse to the Y-axis and to the source-detector axis. A source-detector support on which the source and detector are mounted at opposite sides of the patient position is coupled with a scanning mechanism moving at least one of the patient table and the source-detector support relative to the other to scan the patient position with the narrow angle fan beam in successive scans parallel to the Y-axis in which the source-detector axis is at different angles relative to the patient position as between different ones of successive scans, but in each of the successive scans, an origin of the fan beam in the source is at the same vertical distance from the patient table. The distance between the fan beam origin and the table may be selectively varied between scan passes, in order to vary scan pass magnification.

5600700, Feb 4, 1997

Sep 25, 1995

8/533646

Kristoph D. Krug - Framingham MA
William F. Aitkenhead - Sharon MA
Richard F. Eilbert - Lincoln MA
Jeffrey H. Stillson - Nashua NH
Jay A. Stein - Framingham MA

Vivid Technologies, Inc. - Woburn MA

G01N 2310

378 57

An X-ray inspection device for detecting a specific material of interest (typically contraband, for example, weapons, drugs, money, explosives) in items of various sizes and shapes includes an X-ray source system located at an inspection region and constructed to expose the examined item to at least one beam of X-ray radiation, one or more x-ray detection systems located at the inspection region and constructed to detect x-ray radiation modified by the examined item. The X-ray inspection device also includes one or more dimension detectors constructed to measure a selected dimension of the examined item, an interface system connected to receive X-ray data and dimension data, and a computer programmed to utilize the data for recognition of the specific material of interest and to indicate its presence in the examined item. The X-ray detection systems detect transmitted and/or scattered X-ray radiation utilizing several different geometries. There may be one or more X-ray back-scatter detection systems, or one or more X-ray forward-scatter detection systems detecting X-ray radiation scattered at different angles from different surfaces of the examined item.

5657369, Aug 12, 1997

Apr 25, 1995

8/428044

Jay A. Stein - Framingham MA
Steven Teta - Billerica MA
Richard E. Cabral - Tewksbury MA
Tracy L. Ramsdell - Amherst NH
Tina LeFebvre - Woonsocket RI
Russell J. Gershman - Middleborough MA

Hologic, Inc. - Waltham MA

H05G 100

378208

An x-ray bone densitometry system having an apparatus for positioning body parts is provided. The system includes a patient table having a length extending along a Y-axis and a width extending along an X-axis, a C-arm supporting an x-ray source at one side and an x-ray detector at an opposite side of the table, wherein the source and detector are aligned along a source-detector axis which is transverse to the Y-axis. The source is selectively energized and emits a fan beam of x-rays which conforms to a beam plane which is transverse to the Y-axis and contains the source-detector axis. A forearm positioner is removably supported on the table and includes an arm rest portion positioned at a selected distance along the X-axis from an edge of the table. A hand supporting member is configured to fit within the arm rest portion to maintain the position of a patient's hand in a predetermined shape when the source is energized.

5319547, Jun 7, 1994

Aug 10, 1990

7/566083

Kristoph D. Krug - Framingham MA
Jay A. Stein - Framingham MA
Adam L. Taylor - Boston MA

Vivid Technologies, Inc. - Waltham MA

G06F 1500

364409

A device and method is provided for finding a specific material superimposed on an unknown background when the locations of the specific material and the background are unknown, for example, inside an item of baggage. The invention comprises exposing an area of an item to be inspected to x-rays of two substanitally different energies, making effective use of the characteristic material specific differences in photoelectric effect scattering and Compton scattering, and comparing the pairwise differential attenuation of the x-rays at nearby exposed subareas to determine whether differences in attenuation can be attributed to the presence of different amounts of the specific material overlying the respective subareas. The most probable subareas are indicated on a standard image on a monitor as being the most likely location of the overlying specific material.

4389729, Jun 21, 1983

Dec 15, 1981

6/331100

Jay Stein - Framingham MA

American Science and Engineering, Inc. - Cambridge MA

G01N 2304, H05G 160

378 99

A digital radiography system includes an X-ray source for projecting a beam of X-rays toward and through an object to be examined onto the input face of an image intensifier tube. A multi-hole collimator is disposed between the object and the image intensifier tube for producing a two-dimensional array of spaced pencil beams, and these pencil beams are raster scanned relative to the object being examined and across the input face of the image intensifier tube through small distances corresponding generally to the distance between the holes in the collimator. The succession of images which are produced on the output face of the image intensifier tube during the scanning of the pencil beams are scanned by a video camera whose output signals are digitized and stored as partial images, and the partial images are thereafter interleaved with one another to provide a composite comparatively high resolution image of the object being examined.

5044002, Aug 27, 1991

Mar 7, 1989

7/320156

Jay A. Stein - Framingham MA

Hologic, Inc. - Waltham MA

G01N 2306

378 54

Apparatus for inspecting baggage moved relative to an x-ray beam. The apparatus causes a beam of x-rays to pass through a reference in the course of exposure and detects the presence of the reference material contained within the baggage by matching the effective atomic number of the materials within the bag, with the atomic number of the reference.

5949846, Sep 7, 1999

Feb 3, 1997

8/794615

Jay A. Stein - Framingham MA
Howard P. Weiss - Newton MA
Vincent E. Quinn - Bedford MA
Richard E. Cabral - Tewksbury MA
John A. Shepherd - Natick MA
Kevin E. Wilson - Cambridge MA

Hologic, Inc. - Waltham MA

G01N 2300

378 54

A method of measuring bone mineral density (BMD) of a selected region of bone in a small body portion (such as a limb or extremity), using a mini C-arm x-ray fluoroscopic imaging system to acquire the data from which the BMD is calculated. Apparatus for performing the method includes a tray for positioning the small body portion in the x-ray beam path of the imaging system and a sample of bone of predetermined density supported by the tray in side-by-side relation to the selected region of bone.

6282258, Aug 28, 2001

Jan 19, 1999

9/234034

Jay A. Stein - Framingham MA
Howard P. Weiss - Newton MA
Vincent E. Quinn - Bedford MA
John A. Shepherd - Natick MA
Kevin E. Wilson - Cambridge MA
Joel Weinstein - Framingham MA

Hologic, Inc. - Bedford MA

G01N 2300

378 54

A method of measuring bone mineral density (BMD) of a selected region of bone in a small body portion (such as a limb or extremity), using a mini C-arm x-ray fluoroscopic imaging system to acquire the data from which the BMD is calculated. Apparatus for performing the method includes a tray for positioning the small body portion in the x-ray beam path of the imaging system and a sample of bone of predetermined density supported by the tray in side-by-side relation to the selected region of bone.

5132995, Jul 21, 1992

Aug 7, 1990

7/564156

Jay A. Stein - Framingham MA

Hologic, Inc. - Waltham MA

G01N 2306

378 56

X-ray analysis apparatus and related method including a bone densitometer apparatus, in which detectors are translatable in the plane of the fan beam for each scan line position to provide enhanced signal-to-noise ratio and resolution, and detector-to-detector normalization. In this motion, the detectors move relative to an x-ray source and an object or patient. Indexing or moving from one scan line position to the next involves relative movement between the object or patient, and the x-ray source and detectors, which are fixed in relationship to each other during this indexing.