Inventors:
James Leonard Speyer - New York NY
Franco Mario Muggia - Los Angeles CA
Michael David Green - North Carlton, AU
Assignee:
New York University - New York NY
International Classification:
A61K 31495, A61K 3170
Abstract:
Disclosed is a method for preventing cardiotoxicity in a human in need of such preventive treatment, the method including administering an effective amount of a bisdioxopiperazine. Also disclosed is a method for preventing cardiotoxicity induced by the administration of an anthracycline. Further, a tumoricidal, cardioprotective combination of agents is disclosed.