JAMES SAMUEL MALTER
Medical Practice in Madison, WI
License number
Pennsylvania MD033015E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Madison, WI 53711
Pennsylvania
Pennsylvania
Personal information
See more information about JAMES SAMUEL MALTER at radaris.comName
Address
Phone
Madison, WI
3914 Cherokee Dr, Madison, WI 53711
Professional information
Dr. James S Malter, Dallas TX - MD (Doctor of Medicine)
Specialties:
Blood Banking & Transfusion Medicine
Address:
5323 Harry Hines Blvd, Dallas 75390
(214) 648-4020 (Phone), (214) 648-4067 (Fax)
5323 Harry Hines Blvd, Dallas 75390
(214) 648-4020 (Phone), (214) 648-4067 (Fax)
University of Wisconsin Hospital and Clinics
600 Highland Ave, Madison 53792
(608) 263-6400 (Phone), (608) 829-5315 (Fax)
(214) 648-4020 (Phone), (214) 648-4067 (Fax)
5323 Harry Hines Blvd, Dallas 75390
(214) 648-4020 (Phone), (214) 648-4067 (Fax)
University of Wisconsin Hospital and Clinics
600 Highland Ave, Madison 53792
(608) 263-6400 (Phone), (608) 829-5315 (Fax)
Certifications:
Blood Bank & Transfusion Medicine, 1999, Clinical Pathology, 1988
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Washington Center / School of Medicine
Graduated: 1983
Hospital Of The University Of Pennsylvania
Washington Center / School of Medicine
Graduated: 1983
Hospital Of The University Of Pennsylvania
Method To Increase Regulatory Molecule Production
US Patent:
5587300, Dec 24, 1996
Filed:
Apr 26, 1994
Appl. No.:
8/233130
Inventors:
James S. Malter - Madison WI
Assignee:
Wisconsin Ulumni Research Foundation - Madison WI
International Classification:
C12P 2100, C12P 2102, C12N 1500, C12N 1506
US Classification:
435 691
Abstract:
The present invention provides a method to increase the production of a regulatory molecule, i. e. , a molecule that regulates cell behavior, such as a cytokine or a protooncogene, in a population of transfected cells, whether normal (resting or activated) or tumor cells. The method involves mutating a native or "wild type" cDNA sequence that encodes an mRNA sequence for a regulatory molecule to form a mutant cDNA sequence capable of producing a more stable mRNA sequence. Specifically, the method involves mutating a wild type cDNA sequence that encodes an unstable mRNA sequence for the regulatory molecule, wherein the mRNA includes a 3' untranslated region having a destabilizing element comprising an AUUUA sequence, to form a mutant cDNA sequence capable of producing a more stable mRNA sequence, wherein the AUUUA sequence is replaced by AUGUA, AUAUA, GUGUG, AGGGA, GAGAG, or a combination thereof; and transfecting a cell population with the mutant cDNA sequence so that the production of the regulatory molecule is enhanced by the cells.
Methods For Inhibiting Amyloid Precursor Protein And Beta-Amyloid Production And Accumulation
US Patent:
2009023, Sep 24, 2009
Filed:
Feb 12, 2009
Appl. No.:
12/370397
Inventors:
James Malter - Madison WI, US
Cara Westmark - Fitchburg WI, US
Cara Westmark - Fitchburg WI, US
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION - Madison WI
International Classification:
A61K 31/4168, A61K 31/44, G01N 33/53, A61P 25/00
US Classification:
514277, 514389, 435 71
Abstract:
Compositions and uses of mGluRantagonists for the treatment and inhibition of amyloid precursor protein (APP), Aβ protein, and APP proteolytic products in Alzheimer's disease, Fragile X Syndrome, autism, and Down's Syndrome are provided. The invention provides methods for diagnosing Fragile X Syndrome via the assessment of Aβlevels in blood plasma.
Methods For Inhibiting Amyloid Precursor Protein And Beta-Amyloid Production And Accumulation
US Patent:
2013014, Jun 13, 2013
Filed:
May 22, 2012
Appl. No.:
13/477935
Inventors:
James Malter - Madison WI, US
Cara Westmark - Fitchburg WI, US
Cara Westmark - Fitchburg WI, US
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION - Madison WI
International Classification:
G01N 33/68
US Classification:
435 792
Abstract:
Compositions and uses of mGluRantagonists for the treatment and inhibition of amyloid precursor protein (APP), Aβ protein, and APP proteolytic products in Alzheimer's disease, Fragile X Syndrome, autism, and Down's Syndrome are provided. The invention provides methods for diagnosing Fragile X Syndrome via the assessment of Aβlevels in blood plasma.
Blockade Of Pin1 Prevents Cytokine Production By Activated Immune Cells
US Patent:
7417072, Aug 26, 2008
Filed:
May 12, 2006
Appl. No.:
11/383127
Inventors:
James S. Malter - Madison WI, US
Stephane Esnault - Madison WI, US
Zhong-Jian Shen - Madison WI, US
Stephane Esnault - Madison WI, US
Zhong-Jian Shen - Madison WI, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 31/12, A61K 31/122, A61P 11/06, A61P 29/00, C07C 49/00, C07C 50/00
US Classification:
514682, 514690, 524358, 568 37
Abstract:
The invention provides pharmaceutical compositions and methods of treating immunological disorders. The invention also provides pharmaceutical compositions and methods of inducing eosinophil apoptosis, and methods for treating eosinophil-associated disorders comprising inducing eosinophil apoptosis in an individual in need thereof.
Blockade Of Pin1 Prevents Cytokine Production By Activated Immune Cells
US Patent:
2009005, Feb 26, 2009
Filed:
Aug 22, 2008
Appl. No.:
12/197106
Inventors:
James S. Malter - Madison WI, US
Stephane Esnault - Madison WI, US
Zhong-Jian Shen - Madison WI, US
Stephane Esnault - Madison WI, US
Zhong-Jian Shen - Madison WI, US
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION - Madison WI
International Classification:
A61K 39/395, A61K 31/7088, A61K 31/7105, A61K 38/13, A61K 31/436, C12N 5/06, C12Q 1/02
US Classification:
4241301, 514 44, 514682, 514 11, 514291, 435375, 435 29
Abstract:
The invention provides pharmaceutical compositions and methods of treating immunological disorders. The invention also provides pharmaceutical compositions and methods of inducing eosinophil apoptosis, and methods for treating eosinophil-associated disorders comprising inducing eosinophil apoptosis in an individual in need thereof.