JAMES ROBINSON, DDS
Dentist at Elverta Rd, Sacramento, CA

License number
California 19379
Category
Dentist
Type
General Practice
Address
Address 2
4320 Elverta Rd SUITE 3, Sacramento, CA 95843
2050 NORTH 300 WEST #72, Lake Shore, UT 84660
Phone
(916) 727-6453
(916) 727-1442 (Fax)
(530) 409-1021
(801) 794-2179 (Fax)

Organization information

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James Robinson

4320 Elverta Rd, Sacramento, CA 95843

Industry:
Dentist's Office, Offices and Clinics of Dentists, Dentists, ...
Doing business as:
James Robinson MD,DDS
Phone:
(916) 727-6453 (Phone)
Family And General Dentistry:
James Robinson (Family And General Dentistry)

Professional information

James Robinson Photo 1

Hydroxamates As Therapeutic Agents

US Patent:
8026371, Sep 27, 2011
Filed:
Oct 1, 2010
Appl. No.:
12/896535
Inventors:
Erik J. Verner - Belmont CA, US
Martin Sendzik - San Mateo CA, US
Chitra Baskaran - Foster City CA, US
Joseph J. Buggy - Mountain View CA, US
James Robinson - Sacramento CA, US
Assignee:
Pharmacyclics, Inc. - Sunnyvale CA
International Classification:
C07D 263/54, A61K 31/42
US Classification:
548217, 514375
Abstract:
The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.


James Robinson Photo 2

Hydroxamates As Therapeutic Agents

US Patent:
7276612, Oct 2, 2007
Filed:
Apr 6, 2004
Appl. No.:
10/818755
Inventors:
Eric J. Verner - Foster City CA, US
Martin Sendzik - San Mateo CA, US
Chitra Baskaran - Foster City CA, US
Joseph J. Buggy - San Carlos CA, US
James Robinson - Sacramento CA, US
Assignee:
Pharmacyclics, Inc. - Sunnyvale CA
International Classification:
C07D 307/78, A61K 31/34
US Classification:
549467, 5142312, 5142521, 514350, 514383, 514396, 514406, 514419, 514423, 514443, 514469, 544166, 544336, 546229, 546298, 546336, 5482622, 5483351, 548491, 548537, 548560, 548565, 549 57, 549468
Abstract:
The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.


James Robinson Photo 3

Novel Hydroxamates As Therapeutic Agents

US Patent:
2013014, Jun 6, 2013
Filed:
Jan 17, 2013
Appl. No.:
13/744265
Inventors:
Martin SENDZIK - San Mateo CA, US
Chitra BASKARAN - Foster CA, US
Joseph J. BUGGY - Mountain View CA, US
James ROBINSON - Sacramento CA, US
Assignee:
PHARMACYCLICS, INC. - Sunnyvale CA
International Classification:
A61K 31/343, A61K 45/06, A61N 5/10, C07D 307/85
US Classification:
424 852, 514469, 424 941, 514410, 514 193, 424 854, 514365, 514249, 4241331, 424649, 514 34, 514274, 424 857, 514110, 514171, 600 1
Abstract:
The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.


James Robinson Photo 4

Hydroxamates As Therapeutic Agents

US Patent:
7420089, Sep 2, 2008
Filed:
Aug 6, 2007
Appl. No.:
11/834558
Inventors:
Erik J. Verner - Belmont CA, US
Martin Sendzik - San Mateo CA, US
Chitra Baskaran - Foster City CA, US
Joseph J. Buggy - Mountain View CA, US
James Robinson - Sacramento CA, US
Assignee:
Pharmacyclics, Inc. - Sunnyvale CA
International Classification:
C07C 259/04, C07C 239/00, A61K 31/215, A61K 31/19
US Classification:
562622, 560312, 514507, 514575
Abstract:
The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.


James B Robinson Photo 5

James B Robinson, Antelope CA

Specialties:
Dentist
Address:
4320 Elverta Rd, Antelope, CA 95843


James Robinson Photo 6

Nitrogenous Heterocyclic Compounds And Process For Making Nitrogenous Heterocyclic Compounds And Intermediates Thereof

US Patent:
6951937, Oct 4, 2005
Filed:
Jan 8, 2002
Appl. No.:
10/041160
Inventors:
James Kanter - South San Francisco CA, US
Anjali Pandey - Fremont CA, US
James Robinson - Sacramento CA, US
Robert M. Scarborough - Half Moon Bay CA, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61K031/495, C07D487/00, C07D487/04
US Classification:
544284, 51425217
Abstract:
The present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof and a process for making thereof. The compounds have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention also provides intermediate compounds useful in the process, as well as final products produced by the process, and salts or prodrugs thereof. The invention further provides a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases comprising administering an effective amount of a compound according to the invention to a patient in need thereof.


James Robinson Photo 7

Nitrogenous Heterocyclic Compounds And Process For Making Nitrogenous Heterocyclic Compounds And Intermediates Thereof

US Patent:
7709640, May 4, 2010
Filed:
Dec 19, 2005
Appl. No.:
11/313289
Inventors:
James Kanter - South San Francisco CA, US
Anjali Pandey - Fremont CA, US
James Robinson - Sacramento CA, US
Robert M. Scarborough - Half Moon Bay CA, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07D 295/182
US Classification:
544390
Abstract:
The present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof and a process for making thereof. The compounds have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention also provides intermediate compounds useful in the process, as well as final products produced by the process, and salts or prodrugs thereof. The invention further provides a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases comprising administering an effective amount of a compound according to the invention to a patient in need thereof.


James Robinson Photo 8

Nitrogenous Heterocyclic Compounds And Process For Making Nitrogenous Heterocyclic Compounds And Intermediates Thereof

US Patent:
RE43098, Jan 10, 2012
Filed:
Oct 2, 2007
Appl. No.:
11/866275
Inventors:
James Kanter - South San Francisco CA, US
Anjali Pandey - Fremont CA, US
James Robinson - Sacramento CA, US
Robert M. Scarborough - Half Moon Bay CA, US
Carroll Scarborough, legal representative - Half Moon Bay CA, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61K 31/495, C07D 487/00, C07D 487/04, C07D 239/94
US Classification:
544284, 51425217
Abstract:
The present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof and a process for making thereof. The compounds have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention also provides intermediate compounds useful in the process, as well as final products produced by the process, and salts or prodrugs thereof. The invention further provides a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases comprising administering an effective amount of a compound according to the invention to a patient in need thereof.


James Robinson Photo 9

Clean, High-Yield Preparation Of S,S And R,S Amino Acid Isosteres

US Patent:
2005017, Aug 4, 2005
Filed:
Mar 14, 2005
Appl. No.:
11/081106
Inventors:
Aslam Malik - Cameron Park CA, US
Todd Clement - Folsom CA, US
Hasan Palandoken - Woodland CA, US
James Robinson - Sacramento CA, US
Joy Stringer - Carmichael CA, US
Assignee:
Aerojet Fine Chemicals LLC, a Delaware limited liability company - Sacramento CA
International Classification:
A61K031/421, C07D263/04, C07C215/06, C07C211/21, C07C211/15, C07D301/24
US Classification:
514376000, 548229000, 549520000, 564503000, 564509000, 564510000
Abstract:
The present invention provides compounds and methods that can be used to convert the intermmediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.


James Robinson Photo 10

Clean, High-Yield Preparation Of S,S And R,S Amino Acid Isosteres

US Patent:
2003022, Dec 4, 2003
Filed:
Apr 14, 2003
Appl. No.:
10/414541
Inventors:
Aslam Malik - Cameron Park CA, US
Todd Clement - Folsom CA, US
Hasan Palandoken - Woodland CA, US
James Robinson - Sacramento CA, US
Joy Stringer - Carmichael CA, US
Assignee:
Aerojet Fine Chemicals LLC, a Delaware limited liability company - Sacramento CA
International Classification:
C07D301/27, C 07C 2 9/68
US Classification:
549/514000, 564/355000, 564/442000
Abstract:
The present invention provides compounds and methods that can be used to convert the intermmediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.