JAMES R BAKER, MD
Osteopathic Medicine at Frank Lloyd Wright Dr, Ann Arbor, MI

License number

Michigan 4301054776

Professional information

See more information about JAMES R BAKER at trustoria.com

James R Baker, Ann Arbor MI

Specialties:

Allergist

Address:

4260 Plymouth Rd, Ann Arbor, MI 48109
1500 E Medical Center Dr, Ann Arbor, MI 48109
3621 S State St, Ann Arbor, MI 48108

Board certifications:

American Board of Allergy and Immunology Certification in Allergy and Immunology, American Board of Internal Medicine Certification in Internal Medicine, American Board of Internal Medicine Sub-certificate in Diagnostic Laboratory Immunology (Internal Medicine)

James Russell Baker, Ann Arbor MI

Specialties:

Allergy & Immunology, Internal Medicine, Diagnostic Laboratory Immunology, Allergy & Immunology

Work:

C.S. Mott Children's Hospital
1500 E Medical Center Dr, Ann Arbor, MI 48109

Education:

Loyola University Chicago (1978)

Nanoemulsion Vaccines

US Patent:

2008018, Jul 31, 2008

Filed:

Dec 28, 2007

Appl. No.:

11/966763

Inventors:

James R. Baker - Ann Arbor MI, US
Tarek Hamouda - Milan MI, US

Assignee:

The Regents of the University of Michigan - Ann Arbor MI

International Classification:

A61K 39/00, A61P 31/00

US Classification:

4241841

Abstract:

The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods and compositions for the use of nanoemulsion compounds as mucosal adjuvants to induce immunity against environmental pathogens. Accordingly, in some embodiments, the present invention provides nanoemulsion vaccines comprising a nanoemulsion and an inactivated pathogen or protein derived from the pathogen. The present invention thus provides improved vaccines against a variety of environmental and human-released pathogens.

Methods Of Using Nanoemulsion Compositions Having Anti-Inflammatory Activity

US Patent:

2011020, Aug 18, 2011

Filed:

Apr 28, 2011

Appl. No.:

13/096836

Inventors:

James R. Baker - Ann Arbor MI, US

International Classification:

A61K 9/107, A01N 25/00, A01P 3/00, A01P 1/00, A61P 31/00, A61P 33/00, A61P 29/00, B82Y 5/00

US Classification:

424405, 977962, 977906

Abstract:

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, at least one anti-inflammatory agent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

Delivery Systems Comprising Biocompatible And Bioerodable Membranes

US Patent:

2004012, Jun 24, 2004

Filed:

May 30, 2001

Appl. No.:

09/867924

Inventors:

Blake Roessler - Ann Arbor MI, US
James Baker - Ann Arbor MI, US
Anna Bielinska - Ypsilanti MI, US

International Classification:

C08G063/91, C08G063/48, A61F002/00

US Classification:

424/426000, 525/054100

Abstract:

The present invention relates to novel compositions and methods for delivering substances to target tissues and cells by contacting the targets with delivery systems associated with membranes (e.g., biocompatible or bioerodable membranes). More particularly, the present invention is directed to dendrimer-based methods and compositions for use in disease therapies, wound healing, and generally, improved gene transfection and compound delivery to target cells and tissues in vitro and in vivo.

Extended Pick-Up Truck Cab With Configurable Interior Cargo Space

US Patent:

2004018, Sep 30, 2004

Filed:

Mar 26, 2003

Appl. No.:

10/397568

Inventors:

Gordon Heidacker - Bloomfield Hills MI, US
James Baker - Ann Arbor MI, US
Mark Geiger - West Bloomfield MI, US

International Classification:

B62D033/06

US Classification:

296/190080

Abstract:

An extended cab for a pick-up truck includes an interior cargo storage space between a rearwardmost portion of a rear seat and the rear wall of the cab.

Compositions For Inactivating Pathogenic Microorganisms, Methods Of Making The Compositions, And Methods Of Use Thereof

US Patent:

2006025, Nov 9, 2006

Filed:

Mar 16, 2005

Appl. No.:

11/080629

Inventors:

Theodore Annis - Ann Arbor MI, US
James Baker - Ann Arbor MI, US
Tarek Hamouda - Milan MI, US

International Classification:

A61K 39/12, A61K 39/07, A61K 39/00, A61K 39/38, A61K 9/00

US Classification:

424400000, 424184100, 424246100, 424204100, 977906000

Abstract:

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

Thyroid Peroxidase Epitopic Regions

US Patent:

5998153, Dec 7, 1999

Filed:

Nov 8, 1994

Appl. No.:

8/313200

Inventors:

James R. Baker - Ann Arbor MI
Ronald J. Koenig - Ann Arbor MI

Assignee:

The Regents of the University of Michigan - Ann Arbor MI

International Classification:

G01N 33564, G01N 33573, A61K 3843

US Classification:

435 721

Abstract:

Specific epitopic regions of thyroid peroxidase (TPO), a thyroid specific membrane autoantigen, have been identified within amino acid residues 456 to 933, 517 to 630, and 633 to 933 of the protein (SEQ ID NO:1), with at least one distinct binding region within TPO located from amino acid residues 592 to 613 (SEQ ID NO:3). The identification and production of these localized epitopes/epitopic regions provide specific diagnostic reagents for autoimmune thyroid disease.

Dendrimer Based Compositions And Methods Of Using The Same

US Patent:

2009010, Apr 23, 2009

Filed:

Aug 25, 2005

Appl. No.:

11/661465

Inventors:

Istvan J. Majoros - Ypsilanti MI, US
Thommey P. Thomas - Dexter MI, US
James R. Baker - Ann Arbor MI, US
Zhengyi Cao - Ypsilanti MI, US
Jolanta F. Kukowska-Latallo - Ann Arbor MI, US

International Classification:

A61K 47/48, C08G 69/26, A61P 35/00, A61K 31/519, A61K 51/06, A61K 38/00, A61K 49/00, A61K 31/166, A61K 31/675, A61K 31/4375, A61K 31/704, A61K 31/407, A61K 31/7048, A61K 31/138, A61K 31/337, A61K 31/505, A61K 31/7088, A61K 39/395, A61K 39/385

US Classification:

424 185, 528353, 525418, 525 541, 525 542, 514249, 424 181, 514 2, 424 96, 514615, 514110, 514283, 514 34, 514411, 514 27, 514648, 514449, 514274, 514 44, 4241781, 4241841

Abstract:

The present invention relates to novel therapeutic and diagnostic dendrimers. In particular, the present invention is directed to dendrimer based multifunctional compositions and systems for use in disease diagnosis and therapy (e.g., cancer diagnosis and therapy). The compositions and systems comprise one or more components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and monitoring the response to therapy of a cell or tissue (e.g., a tumor).

Hyper Comb-Branched Polymer Conjugates

US Patent:

5919442, Jul 6, 1999

Filed:

Aug 9, 1996

Appl. No.:

8/694787

Inventors:

Rui Yin - Midland MI
Donald A. Tomalia - Midland MI
David M. Hedstrand - Midland MI
Douglas R. Swanson - Midland MI
James R. Baker - Ann Arbor MI
Jolanta F. Kukowska-Latallo - Ann Arbor MI

Assignee:

Dendritech, Inc. - Midland MI
University of Michigan - Ann Arbor MI

International Classification:

A61K 3174, A01N 2510

US Classification:

424 7818

Abstract:

A novel class of hyper comb-branched polymers conjugated with carried materials are disclosed.