Inventors:
Istvan J. Majoros - Ypsilanti MI, US
Thommey P. Thomas - Dexter MI, US
James R. Baker - Ann Arbor MI, US
Zhengyi Cao - Ypsilanti MI, US
Jolanta F. Kukowska-Latallo - Ann Arbor MI, US
International Classification:
A61K 47/48, C08G 69/26, A61P 35/00, A61K 31/519, A61K 51/06, A61K 38/00, A61K 49/00, A61K 31/166, A61K 31/675, A61K 31/4375, A61K 31/704, A61K 31/407, A61K 31/7048, A61K 31/138, A61K 31/337, A61K 31/505, A61K 31/7088, A61K 39/395, A61K 39/385
US Classification:
424 185, 528353, 525418, 525 541, 525 542, 514249, 424 181, 514 2, 424 96, 514615, 514110, 514283, 514 34, 514411, 514 27, 514648, 514449, 514274, 514 44, 4241781, 4241841
Abstract:
The present invention relates to novel therapeutic and diagnostic dendrimers. In particular, the present invention is directed to dendrimer based multifunctional compositions and systems for use in disease diagnosis and therapy (e.g., cancer diagnosis and therapy). The compositions and systems comprise one or more components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and monitoring the response to therapy of a cell or tissue (e.g., a tumor).