James Patrick Graham
Accountancy at Bear Mtn Dr, Boulder, CO
License number
Colorado 11278
Issued Date
Mar 30, 1988
Renew Date
Dec 1, 2015
Expiration Date
Nov 30, 2017
Type
Certified Public Accountant
Address
Address
1395 Bear Mountain Dr #100, Boulder, CO 80305
Professional information
Pyrimidyl Cyclopentanes As Akt Protein Kinase Inhibitors
US Patent:
2014008, Mar 20, 2014
Filed:
Nov 21, 2013
Appl. No.:
14/086717
Inventors:
James M. Graham - Boulder CO, US
Martin F. Hentemann - Boulder CO, US
Nicholas C. Kallan - Boulder CO, US
Ian S. Mitchell - Boulder CO, US
Stephen T. Schlachter - Boulder CO, US
Keith L. Spencer - Boulder CO, US
Dengming Xiao - Boulder CO, US
Rui Xu - Boulder CO, US
Mike Welch - Boulder CO, US
Jun Liang - South San Francisco CA, US
Brian S. Safina - South San Francisco CA, US
Martin F. Hentemann - Boulder CO, US
Nicholas C. Kallan - Boulder CO, US
Ian S. Mitchell - Boulder CO, US
Stephen T. Schlachter - Boulder CO, US
Keith L. Spencer - Boulder CO, US
Dengming Xiao - Boulder CO, US
Rui Xu - Boulder CO, US
Mike Welch - Boulder CO, US
Jun Liang - South San Francisco CA, US
Brian S. Safina - South San Francisco CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
Array BioPharma Inc. - Boulder CO
Array BioPharma Inc. - Boulder CO
International Classification:
C07D 403/12, C07D 403/14, C07D 409/14, C07D 413/12, C07D 401/12, C07D 405/14
US Classification:
5142345, 544253, 51425216, 544116
Abstract:
The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof.Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.