Inventors:
Longgui Wang - Flushing NY, US
Xiao Liu - Flushing NY, US
Lian Mo - Palo Alto CA, US
Simon Mencher - New York NY, US
James McCarron - New York NY, US
International Classification:
A61K031/404
Abstract:
The invention relates to pharmaceutical compositions and methods of treating inflammatory-related diseases associated with pro-inflammatory cytokine expression and/or reduced expression of anti-inflammatory cytokines. The method typically comprises administration of one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, such as, Meisoindigo and NATURA. Preferably the pharmaceutical composition comprises one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, an anti-inflammatory agent, and a pharmaceutically acceptable carrier.