Inventors:
Simon Foster - Hathersage, GB
James Mond - Silver Spring MD, US
Simon Clarke - Sheffield, GB
Philip McDowell - Middlesex, GB
Kristy Brummel - Sheffield, GB
Assignee:
University of Sheffield - Sheffield
Biosynexus Incorporated - Gaithersburg MD
International Classification:
A61K 39/085, A61K 39/00, C12P 21/04, C07H 21/04, C07K 14/00
US Classification:
4242431, 4242341, 4241841, 530350, 530300, 536 237, 4353201, 4352521, 435199, 435 697
Abstract:
A method for the identification of antigenic polypeptides, typically opsonic antigens, expressed by pathogenic microbes; vaccines comprising said antigens; and therapeutic antibodies directed to said antigenic polypeptides.