JAMES LUPSKI, MD., PHD
Medical Practice at Fannin St, Houston, TX
License number
Texas H5185
Category
Medical Practice
Type
Clinical Genetics (M.D.)
License number
Texas H5185
Category
Medical Practice
Type
Pediatrics
Address
Address
6701 Fannin St, Houston, TX 77030
Phone
(832) 822-4280
(832) 825-4294 (Fax)
(832) 825-4294 (Fax)
Personal information
See more information about JAMES LUPSKI at radaris.comName
Address
Phone
11102 Ashcroft Dr, Houston, TX 77096
11102 Ashcroft Dr, Houston, TX 77096
Organization information
See more information about JAMES LUPSKI at bizstanding.comKleberg Genetic Clinic - James Lupski MD
6701 Fannin St STE 1560, Houston, TX 77030
Categories:
Physicians & Surgeons
Site:
Phone:
(832) 822-4280 (Phone)
Specialties:
Medical
Products:
Health Insurance, Neonatal & Newborn Care
Additional:
DEPARTMENT OF PEDIATRICS
James Lupski MD,PHD
6701 Fannin St, Houston, TX 77030
Industry:
Genetic Medicine, Pediatrician
Phone:
(832) 822-4280 (Phone)
Description:
There are 19 doctors at this site. Surgery is not performed at this site.
James R. Lupski
Professional information
See more information about JAMES LUPSKI at trustoria.com
Dr. James Lupski, Houston TX - MD (Doctor of Medicine)
Dr. James Lupski, Houston TX - MD (Doctor of Medicine)
Address:
Texas Childrens Hospital General
6701 Fannin St SUITE 1560, Houston 77030
(832) 822-4280 (Phone)
Texas Childrens Hospital General
6701 Fannin St SUITE 1560, Houston 77030
(832) 822-4280 (Phone)
6701 Fannin St SUITE 1560, Houston 77030
(832) 822-4280 (Phone)
Texas Childrens Hospital General
6701 Fannin St SUITE 1560, Houston 77030
(832) 822-4280 (Phone)
Education:
Medical Schools
New York University School Of Medicine
Graduated: 1985
New York University School Of Medicine
Graduated: 1985
Nucleic Acid And Amino Acid Sequences For Atp-Binding Cassette Transporter And Methods Of Screening For Agents That Modify Atp-Binding Cassette Transporter
Nucleic Acid And Amino Acid Sequences For Atp-Binding Cassette Transporter And Methods Of Screening For Agents That Modify Atp-Binding Cassette Transporter
US Patent:
6713300, Mar 30, 2004
Filed:
Feb 27, 1998
Appl. No.:
09/032438
Inventors:
Rando Allikmets - Frederick MD
Kent L. Anderson - Houston TX
Michael Dean - Frederick MD
Mark Leppert - Salt Lake City UT
Richard A. Lewis - Houston TX
Yixin Li - Houston TX
James R. Lupski - Houston TX
Jeremy Nathans - Baltimore MD
Amir Rattner - Baltimore MD
Noah F. Shroyer - Houston TX
Nanda Singh - Salt Lake City UT
Philip Smallwood - Woodbine MD
Hui Sun - Baltimore MD
Kent L. Anderson - Houston TX
Michael Dean - Frederick MD
Mark Leppert - Salt Lake City UT
Richard A. Lewis - Houston TX
Yixin Li - Houston TX
James R. Lupski - Houston TX
Jeremy Nathans - Baltimore MD
Amir Rattner - Baltimore MD
Noah F. Shroyer - Houston TX
Nanda Singh - Salt Lake City UT
Philip Smallwood - Woodbine MD
Hui Sun - Baltimore MD
Assignee:
University of Utah Research Foundation - Salt Lake City UT
Baylor College of Medicine - Houston TX
Johns Hopkins University - Baltimore MD
The United States of America as represented by the Department of Health and Human Services - Washington DC
Baylor College of Medicine - Houston TX
Johns Hopkins University - Baltimore MD
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
C12N 1500
US Classification:
435325, 435 691, 4353201, 435455, 536 231, 536 235
Abstract:
The present invention provides nucleic acid and amino acid sequences of an ATP binding cassette transporter and mutated sequences thereof associated with macular degeneration. Methods of detecting agents that modify ATP-binding cassette transporter comprising combining purified ATP binding cassette transporter and at least one agent suspected of modifying the ATP binding cassette transporter an observing a change in at least one characteristic associated with ATP binding cassette transporter. Methods of detecting macular degeneration is also embodied by the present invention.
Antisense Oligonucleotide Antibiotics Complementary To The Macromolecular Synthesis Operon, Methods Of Treating Bacterial Infections And Methods For Identification Of Bacteria
Antisense Oligonucleotide Antibiotics Complementary To The Macromolecular Synthesis Operon, Methods Of Treating Bacterial Infections And Methods For Identification Of Bacteria
US Patent:
5294533, Mar 15, 1994
Filed:
Aug 23, 1990
Appl. No.:
7/572191
Inventors:
James R. Lupski - Houston TX
Leonard Katz - Waukegan IL
Leonard Katz - Waukegan IL
Assignee:
Baylor College of Medicine - Houston TX
Abbott Laboratories - Abbott Park IL
Abbott Laboratories - Abbott Park IL
International Classification:
C21Q 168, C12N 1500, C12N 1511
US Classification:
435 6
Abstract:
A method of interrupting the expression of a macromolecular synthesis operon in bacteria comprising the step of binding an antisense oligonucleotide to a single stranded DNA or to a mRNA transcribed from the macromolecular synthesis operon. The antisense oligonucleotide can be either sequence specific to a unique intergenic sequence or a sequence specific to a bacterial homologous sequence. By interrupting the expression of the macromolecular synthesis operon bacterial infections can be treated. Specific antisense oligonucleotides are disclosed. The ability of the antisense oligonucleotide to bind the mRNA or single stranded DNA also allows the identification of the bacteria by using a unique intergenic antisense oligonucleotide to bind to the single stranded DNA or to the mRNA transcribed from the macromolecular synthesis operon. A method for competitively inhibiting the protein products of the MMS operon with oligonucleotides is also disclosed. Methods of identifying unique intergenic sequence is also disclosed.
Nucleic Acid And Amino Acid Sequences For Atp-Binding Cassette Transporter And Methods Of Screening For Agents That Modify Atp-Binding Cassette Transporter
Nucleic Acid And Amino Acid Sequences For Atp-Binding Cassette Transporter And Methods Of Screening For Agents That Modify Atp-Binding Cassette Transporter
US Patent:
7141420, Nov 28, 2006
Filed:
Jan 10, 2003
Appl. No.:
10/340097
Inventors:
Rando Allikmets - Frederick MD, US
Kent L. Anderson - Houston TX, US
Michael Dean - Frederick MD, US
Mark Leppert - Salt Lake City UT, US
Richard A. Lewis - Houston TX, US
Yixin Li - Houston TX, US
James R. Lupski - Houston TX, US
Jeremy Nathans - Baltimore MD, US
Amir Rattner - Baltimore MD, US
Noah F. Shroyer - Houston TX, US
Nanda Singh - Salt Lake City UT, US
Philip Smallwood - Woodbine MD, US
Hui Sun - Baltimore MD, US
Kent L. Anderson - Houston TX, US
Michael Dean - Frederick MD, US
Mark Leppert - Salt Lake City UT, US
Richard A. Lewis - Houston TX, US
Yixin Li - Houston TX, US
James R. Lupski - Houston TX, US
Jeremy Nathans - Baltimore MD, US
Amir Rattner - Baltimore MD, US
Noah F. Shroyer - Houston TX, US
Nanda Singh - Salt Lake City UT, US
Philip Smallwood - Woodbine MD, US
Hui Sun - Baltimore MD, US
Assignee:
University of Utah Research Foundation - Salt Lake City UT
Baylor College of Medicine - Houston TX
John Hopkins University - Baltiomore MD
The United States of America as represented by the Department of Health and Human Services - Washington DC
Baylor College of Medicine - Houston TX
John Hopkins University - Baltiomore MD
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
C12N 5/00, C12N 15/00, C12N 15/63, C07H 21/02, C07H 21/04, C12P 21/06, C07K 1/00
US Classification:
435325, 435 691, 4353201, 435455, 536 231, 536 235, 530350
Abstract:
The present invention provides nucleic acid and amino acid sequences of an ATP binding cassette transporter and mutated sequences thereof associated with macular degeneration. Methods of detecting agents that modify ATP-binding cassette transporter comprising combining purified ATP binding cassette transporter and at least one agent suspected of modifying the ATP binding cassette transporter an observing a change in at least one characteristic associated with ATP binding cassette transporter. Methods of detecting macular degeneration is also embodied by the present invention.
Methods Of Gene Therapy Using Nucleic Acid Sequences For Atp-Binding Cassette Transporter
Methods Of Gene Therapy Using Nucleic Acid Sequences For Atp-Binding Cassette Transporter
US Patent:
8129353, Mar 6, 2012
Filed:
Dec 11, 2006
Appl. No.:
11/636909
Inventors:
Rando Allikmets - Frederick MD, US
Kent L. Anderson - Houston TX, US
Michael Dean - Frederick MD, US
Mark Leppert - Salt Lake City UT, US
Richard A. Lewis - Houston TX, US
Yixin Li - Houston TX, US
James R. Lupski - Houston TX, US
Jeremy Nathans - Baltimore MD, US
Amir Rattner - Baltimore MD, US
Noah F. Shroyer - Houston TX, US
Nanda Singh - Salt Lake City UT, US
Philip Smallwood - Woodbine MD, US
Hui Sun - Baltimore MD, US
Kent L. Anderson - Houston TX, US
Michael Dean - Frederick MD, US
Mark Leppert - Salt Lake City UT, US
Richard A. Lewis - Houston TX, US
Yixin Li - Houston TX, US
James R. Lupski - Houston TX, US
Jeremy Nathans - Baltimore MD, US
Amir Rattner - Baltimore MD, US
Noah F. Shroyer - Houston TX, US
Nanda Singh - Salt Lake City UT, US
Philip Smallwood - Woodbine MD, US
Hui Sun - Baltimore MD, US
Assignee:
Baylor College of Medicine - Houston TX
John Hopkins University - Baltimore MD
The United States of America as represented by the Secretary, Department of Health and Human Services - Washington DC
University of Utah Research Foundation - Salt Lake City UT
John Hopkins University - Baltimore MD
The United States of America as represented by the Secretary, Department of Health and Human Services - Washington DC
University of Utah Research Foundation - Salt Lake City UT
International Classification:
A61K 48/00, A61K 38/43, C07H 21/02
US Classification:
514 44R, 536 231, 424 941
Abstract:
The present invention provides nucleic acid and amino acid sequences of an ATP binding cassette transporter and mutated sequences thereof associated with macular degeneration. Methods of detecting agents that modify ATP-binding cassette transporter comprising combining purified ATP binding cassette transporter and at least one agent suspected of modifying the ATP binding cassette transporter an observing a change in at least one characteristic associated with ATP binding cassette transporter. Methods of detecting macular degeneration is also embodied by the present invention.
Fingerprinting Bacterial Strains Using Repetitive Dna Sequence Amplification
Fingerprinting Bacterial Strains Using Repetitive Dna Sequence Amplification
US Patent:
5523217, Jun 4, 1996
Filed:
May 25, 1994
Appl. No.:
8/248848
Inventors:
James R. Lupski - Houston TX
Thearith Koeuth - Houston TX
James Versalovic - Houston TX
Thearith Koeuth - Houston TX
James Versalovic - Houston TX
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12P 1934, C12Q 168, C07H 2104
US Classification:
435 912
Abstract:
Oligonucleotide primers and methods for identifying strains of bacteria by genomic fingerprinting are described. The methods are applicable to a variety of samples. The testing procedure includes amplifying the bacterial DNA in the sample to be tested by adding a pair of outwardly-directed primers to the sample. The primers are capable of hybridizing to repetitive DNA sequences in the bacterial DNA and extending outwardly from one hybridizable repetitive sequence to another hybridizable repetitive sequence. After amplification the extension products are separated by size and the specific strain of bacteria is determined by measuring the pattern of sized extension products. The procedure to identify strains of bacteria by fingerprinting has a variety of uses including: identifying bacteria in infections, agriculture and horticulture plots, bioremediation, food monitoring, production monitoring and quality assurance and quality control.
Methods Of Screening For Agents That Delay A Cell Cycle And Compositions Comprising Era And An Analogue Of Wild-Type Era
Methods Of Screening For Agents That Delay A Cell Cycle And Compositions Comprising Era And An Analogue Of Wild-Type Era
US Patent:
6132954, Oct 17, 2000
Filed:
Aug 20, 1997
Appl. No.:
8/915498
Inventors:
James R. Lupski - Houston TX
Robert A. Britton - Cambridge MA
Donald L. Court - Frederick MD
Bradford S. Powell - Frederick MD
Robert A. Britton - Cambridge MA
Donald L. Court - Frederick MD
Bradford S. Powell - Frederick MD
Assignee:
Baylor College of Medicine - Houston TX
The United States of America as represented by the Department of Health
and Human Services - Washington DC
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
C12Q 168, G01N 3353
US Classification:
435 4
Abstract:
The present invention provides for methods of screening for agents which delay the cell cycle and methods of delaying the cell cycle. Analogues of Era having arginine, histidine, or lysine at amino acid codon 17 are embodied by the present invention. Human and other homologs of bacterial Era amino acid and nucleic acid sequences are provided in the present invention. Vectors, host cells, protein preparations, cell cultures, and compositions comprising said analogue are also set forth in the present invention.
Methods Of Gene Therapy Using Nucleic Acid Sequences For Atp-Binding Cassette Transporter
Methods Of Gene Therapy Using Nucleic Acid Sequences For Atp-Binding Cassette Transporter
US Patent:
2012004, Feb 16, 2012
Filed:
Jun 2, 2011
Appl. No.:
13/151375
Inventors:
Rando Allikmets - Frederick MD, US
Kent L. Anderson - Houston TX, US
Michael Dean - Frederick MD, US
Mark Leppert - Salt Lake City UT, US
Richard A. Lewis - Houston TX, US
Yixin Li - Houston TX, US
James R. Lupski - Houston TX, US
Jeremy Nathans - Baltimore MD, US
Amir Rattner - Baltimore MD, US
Noah F. Shroyer - Houston TX, US
Nanda Singh - Salt Lake City UT, US
Philip Smallwood - Woodbine MD, US
Hui Sun - Baltimore MD, US
Kent L. Anderson - Houston TX, US
Michael Dean - Frederick MD, US
Mark Leppert - Salt Lake City UT, US
Richard A. Lewis - Houston TX, US
Yixin Li - Houston TX, US
James R. Lupski - Houston TX, US
Jeremy Nathans - Baltimore MD, US
Amir Rattner - Baltimore MD, US
Noah F. Shroyer - Houston TX, US
Nanda Singh - Salt Lake City UT, US
Philip Smallwood - Woodbine MD, US
Hui Sun - Baltimore MD, US
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12N 1/21, C12N 15/11, C12N 15/63, C12N 5/10, C12N 1/19
US Classification:
435348, 435349, 435358, 435363, 435367, 4352523, 43525231, 43525233, 43525234, 4352542, 43525421, 4353201, 536 231
Abstract:
The present invention provides nucleic acid and amino acid sequences of an ATP binding cassette transporter and mutated sequences thereof associated with macular degeneration. Methods of detecting agents that modify ATP-binding cassette transporter comprising combining purified ATP binding cassette transporter and at least one agent suspected of modifying the ATP binding cassette transporter an observing a change in at least one characteristic associated with ATP binding cassette transporter. Methods of detecting macular degeneration is also embodied by the present invention.
Fig4 Gene Mutations In Neurodegeneration
Fig4 Gene Mutations In Neurodegeneration
US Patent:
2010014, Jun 10, 2010
Filed:
Apr 25, 2008
Appl. No.:
12/597539
Inventors:
Miriam Meisler - Ann Arbor MI, US
James R. Lupski - Houston TX, US
Clement Chow - Ann Arbor MI, US
James R. Lupski - Houston TX, US
Clement Chow - Ann Arbor MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
BAYLOR COLLEGE OF MEDICINE - Houston TX
BAYLOR COLLEGE OF MEDICINE - Houston TX
International Classification:
A61K 49/00, C12Q 1/68, G01N 33/53
US Classification:
424 91, 435 6, 435 71
Abstract:
The present invention relates to neuropathy, in particular to mutations in the FI G4 gene. The present invention also provides assays for the detection of variant FIG4 alleles, and assays for detecting FIG4 polymorphisms and mutations associated with disease states.
Defects In Periaxin Associated With Myelinopathies
Defects In Periaxin Associated With Myelinopathies
US Patent:
7537899, May 26, 2009
Filed:
Aug 14, 2007
Appl. No.:
11/838500
Inventors:
James R. Lupski - Houston TX, US
Hiroshi Takashima - Houston TX, US
Hiroshi Takashima - Houston TX, US
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12Q 1/68, C12P 19/34, C07H 21/04
US Classification:
435 6, 435 912, 536 231, 536 2344
Abstract:
The present invention relates to defects in periaxin (PRX) associated with myelinopathies, including Charcot-Marie-Tooth syndrome and/or Dejerine-Sottas syndrome. Unrelated individuals having a myelinopathy from Dejerine-Sottas syndrome have recessive PRX mutations. The PRX locus maps to a region associated with a severe autosomal recessive demyelinating neuropathy and is also syntenic to the Prx location on murine chromosome 7.