Inventors:
Gilles Cloutier - Chapel Hill NC, US
James Crow - Chapel Hill NC, US
Michael Wade - Chapel Hill NC, US
Richard E. Parker - Spring Hill TN, US
James E. Loyd - Nashville TN, US
International Classification:
A61K 31/192
Abstract:
The present invention describes novel methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of ischemic lesions, such as digital ulcers, in subjects with scleroderma (including systemic sclerosis), Buerger's disease, Raynaud's disease, Raynaud's phenomenon and/or other conditions that cause such lesions. The invention also relates to kits for treatment and/or prevention of ischemic lesions, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.