Inventors:
James L. Schaller - Naples FL, US
Ben Briggs - Coatesville PA, US
International Classification:
A61K 31/7076, A61K 31/455, A61K 31/4415
US Classification:
514 46, 514 45, 514350, 514356
Abstract:
Disclosed herein are topical formulations for treating depression with S adenosyl methionine (SAM-e) The topical formulations contain at least 35% wt/wt of SAM-e partially dissolved in aqueous and lipophilic phases of an emulsion and the emulsion is stable from separation of phases for a period of at least 30 days despite the high concentration of SAM-e. Also provided are methods for making such compositions and methods of treating depression using the same.