Inventors:
James L. Levin - Wellesley MA
Jean F. Regal - Duluth MN
Carol A. Toth - Sharon MA
Assignee:
Avant Immunotherpeutics, Inc. - Needham MA
Regents of the University of Minnesota - Minneapolis MN
International Classification:
A61K 3817, A61K 912, A61K 914
Abstract:
A method is disclosed for treating diseases or disorders involving complement by pulmonary administration of complement inhibitory proteins such as soluble complement receptor type 1 (sCR1). The present invention relates to the direct treatment of certain complement related disorders by administering complement inhibitory proteins via the pulmonary route, in particular, by direct delivery to the lungs by aerosolization of a complement inhibitory protein and subsequent inhalation.