JAMES FROST
Speech Language Pathology at 30 St, Baltimore, MD
License number
Maryland 01195L
Category
Speech Language Pathology
Type
Speech-Language Pathologist
Address
Address
416 E 30Th St, Baltimore, MD 21218
Phone
(410) 889-0727
(410) 889-0729 (Fax)
(410) 889-0729 (Fax)
Personal information
See more information about JAMES FROST at radaris.comName
Address
Phone
4977 Battery Ln APT 620, Bethesda, MD 20814
Professional information
See more information about JAMES FROST at trustoria.com
Non-Invasive Diagnostic Imaging Technology For Mitochondria Using Radiolabeled Lipophilic Salts
Non-Invasive Diagnostic Imaging Technology For Mitochondria Using Radiolabeled Lipophilic Salts
US Patent:
8524193, Sep 3, 2013
Filed:
Feb 6, 2003
Appl. No.:
10/503690
Inventors:
Igal Madar - Baltimore MD, US
Hayden T. Ravert - Bel Air MD, US
Robert Francis Dannals - Sparks MD, US
Ursula A. Scheffel - Baltimore MD, US
James J. Frost - Baltimore MD, US
Hayden T. Ravert - Bel Air MD, US
Robert Francis Dannals - Sparks MD, US
Ursula A. Scheffel - Baltimore MD, US
James J. Frost - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 51/00, A61M 36/14
US Classification:
424 189, 424 111, 424 165, 424 181, 424 185
Abstract:
The invention provides lipophilic salts, particularly, lipophilic salts comprising a pharmaceutically acceptable anion and at least one phosphonium or ammonium cation. In certain embodiments, the cation is labeled with one or more radioisotopes. The lipophilic salts of the invention exhibit an affinity for dysfunctional mitochondria, and are useful for the imaging of cardiovascular diseases and disorders. The invention also provides pharmaceutical compositions and methods of using the lipophilic salts.
Non-Invasive Diagnostic Imaging Technology For Mitochondria Dysfunction Using Radiolabeled Lipophilic Salts
Non-Invasive Diagnostic Imaging Technology For Mitochondria Dysfunction Using Radiolabeled Lipophilic Salts
US Patent:
7112318, Sep 26, 2006
Filed:
Feb 6, 2003
Appl. No.:
10/360566
Inventors:
Igal Madar - Baltimore MD, US
Hayden T. Ravert - Bel Air MD, US
Robert Francis Dannals - Sparks MD, US
Ursula A. Scheffel - Baltimore MD, US
James J. Frost - Baltimore MD, US
Hayden T. Ravert - Bel Air MD, US
Robert Francis Dannals - Sparks MD, US
Ursula A. Scheffel - Baltimore MD, US
James J. Frost - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 51/00, A61M 36/14
US Classification:
424 189, 424 111, 424 165, 424 177, 424 181, 424 185, 424 91
Abstract:
The invention provides a series of lipophilic phosphonium cations (PhCs) labeled with F for non-invasive assessment of ΔΨm, lipophilic ammonium cation analogs of the PhCs, and methods of using same for imaging and detection of mitochondrial-related pathologies in patients using PET or SPECT.
Speech Language Pathology licenses in Maryland
NANCY ELIZABETH SHAW-HART, Speech Language Pathology, 4000 Old Court Rd STE 202, Baltimore, MD 21208