Inventors:
Quarraisha Abdool Karim - Durban, ZA
Salim S. Abdool Karim - Durban, ZA
Ayesha Kharsany - Durban, ZA
Tomas Cihlar - Foster City CA, US
James F. Rooney - Foster City CA, US
International Classification:
A61K 31/675, A61K 9/00
Abstract:
The present invention relates to formulations of antiviral compounds, in particular [2-(6-amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid (tenofovir, PMPA), suitable for topical application, and to their use in the reduction of or prevention of acquisition and transmission of herpes simplex virus.