Inventors:
James C. Mannion - Plainsboro NJ, US
Scott L. Dax - Landenberg PA, US
Duncan Euan MacIntyre - Scotch Plains NJ, US
Francis John Golder - Philadelphia PA, US
James Francis McLeod - Hatboro PA, US
International Classification:
A61K 31/53, A61P 11/00, A61K 31/505, A61K 31/519, C07D 251/54, C07D 239/50
US Classification:
514245, 544196, 544323, 514275, 5142651
Abstract:
The present invention includes compositions that are useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention.