Inventors:
Robert Mays - Cleveland Heights OH, US
Robert J. Deans - Riverside CA, US
David C. Hess - Martinez GA, US
James E. Carroll - Augusta GA, US
Cesar V. Borlongan - Augusta GA, US
Assignee:
ATHERSYS, INC. - Cleveland OH
International Classification:
A61K 39/395, A61K 35/14, A61K 35/407, A61K 35/28, A61K 35/50, A61P 25/00
Abstract:
The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.