Inventors:
Atul J. Shukla - Cordova TN, US
James R. Johnson - Germantown TN, US
Yichun Sun - Gaithersburg MD, US
Yingxu Peng - Pennington NJ, US
Shipeng Yu - Memphis TN, US
Wen Qu - Memphis TN, US
Timothy D. Mandrell - Memphis TN, US
International Classification:
A61K 31/4355, A61K 31/445
Abstract:
Parenteral extravascular administration of a composition containing an analgesic medication of low water solubility that is dissolved, suspended, or emulsified in a solvent system results in the deposition of the analgesic medication at the site of administration and provides a controlled release of the analgesic medication from the site and a prolonged analgesia that may persist for several days following administration.