JAMES DASHUAN WILLIAMS
Social Work at Prospect St, East Brunswick, NJ
License number
New Jersey 44SL06280800
Category
Social Work
Type
Social Worker
Address
Address
2
15 W Prospect St, East Brunswick, NJ 08816
16206 Skylands Ct, East Freehold, NJ 07728
16206 Skylands Ct, East Freehold, NJ 07728
Phone
(732) 254-0600
(732) 254-8606 (Fax)
(908) 917-1076
(732) 254-8606 (Fax)
(908) 917-1076
Professional information
Solubilization Of Rafoxanide
US Patent:
4128632, Dec 5, 1978
Filed:
Feb 13, 1978
Appl. No.:
5/876968
Inventors:
James B. Williams - Freehold NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 3179, A61K 31165
US Classification:
424 80
Abstract:
A soluble complex of an insoluble drug, exemplified by Rafoxanide is formed with polyvinylpyrrolidone and water. The complex is formed by combining the insoluble drug and polyvinylpyrrolidone in a suitable water miscible organic solvent, preferably acetone or glycerolformal, and water. The complex is formed in situ. The solvent may be removed, if desired, and the complex remains in aqueous solution. The aqueous solution is then suitable for injection and may be used to treat fasciola or liver fluke infections.
Non-Aqueous Ivermectin Formulation With Improved Antiparasitic Activity
US Patent:
4853372, Aug 1, 1989
Filed:
Nov 28, 1986
Appl. No.:
6/935914
Inventors:
James B. Williams - Freehold NJ
Russell U. Nesbitt - Somerville NJ
Russell U. Nesbitt - Somerville NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 3171
US Classification:
514 30
Abstract:
Ivermectin, an antiparasitic agent which is insoluble and unstable in water, is formulated in glycerol formal and propylene glycol. These liquid formulations are suitable for parenteral administration for the treatment of parasitic infections and demonstrate improved efficacy and a broadened spectrum over previous formulations.
Solubilization Of Ivermectin In Water
US Patent:
4389397, Jun 21, 1983
Filed:
Sep 21, 1981
Appl. No.:
6/304124
Inventors:
James B. Williams - Freehold NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 3170
US Classification:
424180
Abstract:
Ivermectin, an antiparasitic agent which is insoluble and unstable in water, is solubilized by the formation of colloidal particles, called micelles, with surface active agents as solubilizers and stabilized by using cosolvents and/or appropriate substrates in the aqueous formulation. The liquid formulations are suitable for use as parenteral or oral administration for the treatment of parasitic infections.