Inventors:
Terence S. Dermody - Brentwood TN, US
Karl W. Boehme - Little Rock AR, US
Mine Ikizler - Nashville TN, US
Gregory J. Wilson - Nashville TN, US
James D. Chappell - Nashville TN, US
International Classification:
C07K 14/14
US Classification:
4241881, 530350, 4353201, 4241921
Abstract:
The present invention provides for modified reoviruses that carry α-helical epitopes from a variety of pathogens, as well as methods of using such modified reoviruses to generate immune responses against those epitopes in hosts.