DR. JAMES C. MATHEWS, D.O.
Osteopathic Medicine at Wake Forest Rd, Durham, NC
License number
North Carolina 036-117010
Category
Osteopathic Medicine
Type
Emergency Medicine
License number
North Carolina 5101018516
Category
Osteopathic Medicine
Type
Emergency Medicine
License number
North Carolina 2011-00660
Category
Osteopathic Medicine
Type
Emergency Medicine
Address
Address
3400 Wake Forest Rd, Durham, NC 27713
Phone
(919) 954-3271
(847) 924-8265
(847) 924-8265
Personal information
See more information about JAMES C. MATHEWS at radaris.comName
Address
Phone
507 Bingham St, Durham, NC 27703
500 Mcmillan Ave, Red Springs, NC 28377
5946 Woodhall, Hickory, NC 28602
6109 Cardinal Dr, New Bern, NC 28560
312 Greenbay Rd, Mooresville, NC 28117
Professional information
Grape Seed Extract And Its Constituents For Use As Cyp2A6 Inhibitors
US Patent:
2009022, Sep 3, 2009
Filed:
Oct 6, 2006
Appl. No.:
12/089466
Inventors:
James Madison Mathews - Durham NC, US
Amy Sue Etheridge - Cary NC, US
Amy Sue Etheridge - Cary NC, US
Assignee:
Nicogen Imc. - Toronto. Ontario CA
Research Triangle Institute - Research Triangle Park NC
Research Triangle Institute - Research Triangle Park NC
International Classification:
A61K 36/87, A61P 35/00, A61P 9/00, A61P 25/34, A61P 11/00
US Classification:
424766
Abstract:
The present invention relates to a use of grape seed extract or its constituents to treat conditions which benefit from an inhibition of cytochrome P450 2A6 (CYP2A6). In particular conditions which benefit from the inhibition of CYP2A6 are conditions which benefit from decreased metabolism of nicotine to cotinine, for example, preventing, reducing or treating smoking, and conditions which benefit from a decrease in the in vivo formation of carcinogens, for example prevention or treatment of cancer.