JAMES BURKE
Vehicle Board in Langhorne, PA

License number
Pennsylvania MV246032
Category
Vehicle Board
Type
Vehicle Salesperson
Address
Address
Langhorne, PA 19053

Professional information

James Burke Photo 1

Architecture &Amp; Planning Professional

Position:
Landscape Architect at JMB Designs
Location:
Greater Philadelphia Area
Industry:
Architecture & Planning
Work:
JMB Designs - Philadelphia, PA since 2010 - Landscape Architect Advanced GeoServices - West Chester, PA 2004 - 2010 - Senior Consultant / Landscape Architect Vollmer Associates - Wilmington, DE 2003 - 2004 - Senior Landscape Architect Bucks County Parks and Recreation - Langhorne, PA 1994 - 2002 - Chief Landscape Architect Ccope Linder Associates - Philadelphia, PA 1986 - 1994 - Project Manager / Landscape Architect Sullivan Associates - Philadelphia, PA 1984 - 1986 - Project Manager / Land Planner Salkin Group - Philadelphia, PA 1980 - 1984 - Land Planner
Education:
Rutgers University, New Brunswick , NJ 1976 - 1979
BS, Environmental Planning and Design


James Burke Photo 2

Trifluoromethyl Ketone Analogs As Selective Cpla2 Inhibitors

US Patent:
6350892, Feb 26, 2002
Filed:
Feb 18, 2000
Appl. No.:
09/507782
Inventors:
Jacques Banville - St-Hubert, CA
Yonghua Gai - Killingworth CT
Graham Johnson - Madison CT
Fred Christopher Zusi - Hamden CT
James R. Burke - Upper Holland PA
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07F 704
US Classification:
556436, 514 63, 514648, 514676, 514709, 556440, 564316, 568 31, 568 43
Abstract:
Selective inhibitors of the cPLA enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula where (R′), p, D, Y, Z, R , R and A are as defined in the specification.


James Burke Photo 3

Modulators Of The P2Y10 Receptor Useful In Altering T Lymphocyte Function

US Patent:
2006025, Nov 16, 2006
Filed:
Jul 20, 2006
Appl. No.:
11/489829
Inventors:
James Burke - Upper Holland PA, US
Violetta Iotzova - Robbinsville NJ, US
International Classification:
A61K 39/395, G01N 33/567, C07K 16/28
US Classification:
424144100, 435007200, 530388220
Abstract:
The present invention relates to modulators of P2Y10. Various modulators are disclosed, including an antibody that binds specifically to P2Y10. The present invention also relates to methods of activating resting T lymphocytes and inhibiting the proliferation of activated T lymphocytes. Methods of upregulating trascription of P2Y10 mRNA in a resting T lymphocyte, methods of inducing expression of P2Y10 on the surface of a resting T lymphocyte and methods of activating a T lymphocyte are disclosed. Also disclosed are pharmaceuticals and methods of treating an immune disease.


James Burke Photo 4

Antibodies Of The P2Y10 Receptor Useful In Altering T Lymphocyte Function

US Patent:
7101962, Sep 5, 2006
Filed:
May 13, 2004
Appl. No.:
10/844736
Inventors:
James R. Burke - Upper Holland PA, US
Violetta Iotzova - Robbinsville NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 39/395
US Classification:
5301431, 4241391, 4241411, 5303879, 5303881, 53038822, 435331, 435334
Abstract:
The present invention relates to modulators of P2Y10. Various modulators are disclosed, including an antibody that binds specifically to P2Y10. The present invention also relates to methods of activating resting T lymphocytes and inhibiting the proliferation of activated T lymphocytes. Methods of upregulating trascription of P2Y10 mRNA in a resting T lymphocyte, methods of inducing expression of P2Y10 on the surface of a resting T lymphocyte and methods of activating a T lymphocyte are disclosed. Also disclosed are pharmaceuticals and methods of treating an immune disease.