JAE JONG KIM
Medical Practice in Ann Arbor, MI
License number
Pennsylvania MD033316L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Ann Arbor, MI 48105
Pennsylvania
Pennsylvania
Professional information
Methods And Composition Of Extended Delivery Of Water Insoluble Drugs
US Patent:
8535716, Sep 17, 2013
Filed:
Apr 1, 2005
Appl. No.:
11/097487
Inventors:
John Hilfinger - Ann Arbor MI, US
Jae Seung Kim - Ann Arbor MI, US
Paul Kijek - Whitmore Lake MI, US
Jae Seung Kim - Ann Arbor MI, US
Paul Kijek - Whitmore Lake MI, US
Assignee:
TSRL, Inc. - Ann Arbor MI
International Classification:
A61K 9/22
US Classification:
424468, 424464, 424465, 424469, 424470
Abstract:
A pharmaceutical composition is provided that includes an active ingredient in the form of a powder or granule, a water soluble high molecular weight excipient and a water insoluble hydrophilic amphiphilic excipient. These ingredients are solution mixed and dried to form a modified pharmaceutical ingredient in simultaneous contact with both the water soluble high molecular weight excipient and the water insoluble hydrophilic amphiphilic excipient. Adjuvants are compacted about the modified pharmaceutical ingredient as well as a release control agent. The release control agent being present at levels from 1 to 40 total weight percent of the pharmaceutical composition.