JACQUELINE F BROMBERG, MD
Osteopathic Medicine at York Ave, New York, NY
License number
New York 190392
Category
Osteopathic Medicine
Type
Medical Oncology
Address
Address
1275 York Ave, New York, NY 10021
Phone
(646) 227-3813
Personal information
See more information about JACQUELINE F BROMBERG at radaris.comName
Address
Phone
9 Lakeville Ln, Plainview, NY 11803
9 Lakeville Ln, Plainview, NY 11803
Professional information
Dr. Jacqueline Bromberg, New York NY - MD (Doctor of Medicine)
Specialties:
Oncology, Medical Oncology
Address:
Memorial Pulmonary Function Group
1275 York Ave SUITE H1307, New York 10065
(212) 639-6450 (Phone)
1275 York Ave SUITE H1307, New York 10065
(212) 639-6450 (Phone)
Certifications:
Internal Medicine, 1994, Medical Oncology, 2010
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Memorial Pulmonary Function Group
1275 York Ave SUITE H1307, New York 10065
Memorial Sloan - Kettering Cancer Center
1275 York Ave, New York 10065
1275 York Ave SUITE H1307, New York 10065
Memorial Sloan - Kettering Cancer Center
1275 York Ave, New York 10065
Education:
Medical School
University Of North Carolina, Chapel Hill, School Of Medicine
Graduated: 1990
Barnes Hosp/Wash U
University Of North Carolina, Chapel Hill, School Of Medicine
Graduated: 1990
Barnes Hosp/Wash U
Jacqueline F Bromberg, New York NY
Specialties:
Oncologist
Address:
1275 York Ave, New York, NY 10065
633 3Rd Ave, New York, NY 10017
633 3Rd Ave, New York, NY 10017
Education:
University of North Carolina, School of Medicine - Doctor of Medicine
University of North Carolina, School of Medicine - Doctor of Philosophy
Barnes-Jewish Hospital - Residency - Internal Medicine
University of North Carolina, School of Medicine - Doctor of Philosophy
Barnes-Jewish Hospital - Residency - Internal Medicine
Board certifications:
American Board of Internal Medicine Sub-certificate in Oncology (Internal Medicine)
Jacqueline F Bromberg, New York NY
Specialties:
General Practice, Internal Medicine, Medical Oncology, Hematology & Oncology
Work:
Memorial Solid Tumor Group
1275 York Ave, New York, NY 10065 Memorial Solid Tumor Group
205 E 64Th St, New York, NY 10065
1275 York Ave, New York, NY 10065 Memorial Solid Tumor Group
205 E 64Th St, New York, NY 10065
Education:
University of North Carolina (1990)
Constitutively Active Transcription Factors And Their Uses For Identifying Modulators Of Activity Including Dysproliferative Cellular Changes
US Patent:
6235873, May 22, 2001
Filed:
Jul 31, 1999
Appl. No.:
9/364970
Inventors:
Jacqueline F. Bromberg - New York NY
Melissa H. Wrzeszczynska - New York NY
Yanxiang Zhao - New York NY
James E. Darnell - Larchmont NY
Melissa H. Wrzeszczynska - New York NY
Yanxiang Zhao - New York NY
James E. Darnell - Larchmont NY
Assignee:
The Rockefeller University - New York NY
International Classification:
A61K 3800, C07K 1400, C08G 6926, C07H 2102
US Classification:
530300
Abstract:
The invention is directed to constitutively active Stat proteins and methods for their preparation. The modified Stat proteins have at least one cysteine residue which may interact with the corresponding cysteine residue on another modified Stat protein to form a dimer. The constitutively active Stat proteins are capable of binding to DNA and activating transcription in the absence of tyrosine phosphorylation. Cell lines expressing the modified Stat protein exhibit a transformed phenotype and are capable of forming tumors in nude mice. Methods are describe utilizing the modified Stat proteins of the invention in the absence and presence of tyrosine phosphorylation in identifying agents capable of modulating Stat protein dimerization, transcriptional activity, and cellular transformation in vitro and in vivo. The invention is also directed to polynucleotides encoding modified, constitutively active Stat proteins.