DR. JACK WESLY MONCRIEF, M.D.
Osteopathic Medicine at 34 St, Austin, TX

4620845, Nov 4, 1986

Jun 28, 1984

6/625801

Robert P. Popovich - Austin TX
Jack W. Moncrief - Austin TX

A61M 300

604 28

The incidence of peritonitis is reduced in continuous ambulatory peritoneal dialysis by irradiating the peritoneum access tube connection with ultraviolet (UV) radiation so as to have an antimicrobial effect on the fluid flow path defined thereby prior to draining and infusion of dialysis fluid therethrough. The apparatus for effecting UV irradiation of the dialysis fluid flow path includes a housing for enclosing the tube connection. Contained inside the housing is a source of UV radiation for irradiating the tube connection. A UV radiation source control circuit establishes the irradiation cycle based on time of exposure. A UV radiation intensity measuring cirucit may also be used to maintain UV source output until a predetermined cumulative UV exposure has been attained.

4503333, Mar 5, 1985

Feb 24, 1983

6/469196

Ralph Kulin - Marengo IL
Jack W. Moncrief - Austin TX
Robert P. Popovich - Austin TX
Ronald C. Stauber - Hawthorne Woods IL

Baxter Travenol Laboratories - Deerfield IL

A61L 210, G21K 508, H01J 3720

2504551

A connector valve for selectively permitting the transfer of fluids therethrough is described. Multiple-way valve means communicates with a plurality of conduits and selectively permits and prevents flow between the conduits. The multiple-way valve means comprises outer walls made of a substantially ultraviolet-transmissive material, with the outer walls of the multiple-way valve means preferably enclosing an elastomeric seal member defining rotatable channel means for communication with differing conduits at differing rotational positions, and also providing a rotatable seal against inner surfaces of the outer walls to maintain an antimicrobial seal of said conduits. The channel means is exposed along its entire length to an inner surface of an outer wall, to facilitate the anitmicrobial effect of ultraviolet radiation. Also, a novel method of practicing continuous ambulatory peritoneal dialysis, and an ultraviolet light applicator, is disclosed.

4412834, Nov 1, 1983

Jun 5, 1981

6/270743

Ralph Kulin - Marengo IL
Jack W. Moncrief - Austin TX
Robert P. Popovich - Austin TX
Ronald C. Stauber - Hawthorne Woods IL

Baxter Travenol Laboratories - Deerfield IL

A61J 700, F16L 3500

604 29

A connector valve for selectively permitting the transfer of fluids therethrough is described. Multiple-way valve means communicates with a plurality of conduits and selectively permits and prevents flow between the conduits. The multiple-way valve means comprises outer walls made of a substantially ultraviolet-transmissive material, with the outer walls of the multiple-way valve means preferably enclosing an elastomeric seal member defining rotatable channel means for communication with differing conduits at differing rotational positions, and also providing a rotatable seal against inner surfaces of the outer walls to maintain an antimicrobial seal of said conduits. The channel means is exposed along its entire length to an inner surface of an outer wall, to facilitate the antimicrobial effect of ultraviolet radiation. Also, a novel method of practicing continuous ambulatory peritoneal dialysis, and an ultraviolet light applicator, is disclosed.

4475900, Oct 9, 1984

Jun 5, 1981

6/270800

Robert P. Popovich - Austin TX
Jack W. Moncrief - Austin TX

A61M 300

604 28

The incidence of peritonitis is reduced in continuous ambulatory peritoneal dialysis by irradiating the peritoneum access tube connection with ultraviolet (UV) radiation so as to have an antimicrobial effect on the fluid flow path defined thereby prior to draining and infusion of dialysis fluid therethrough. The apparatus for effecting UV irradiation of the dialysis fluid flow path includes a housing for enclosing the tube connection. Contained inside the housing is a source of UV radiation for irradiating the tube connection. A UV radiation source control circuit establishes the irradiation cycle based on time of exposure. A UV radiation intensity measuring circuit may also be used to maintain UV source output until a predetermined cumulative UV exposure has been attained.

4239041, Dec 16, 1980

Aug 4, 1978

5/931098

Robert P. Popovich - Austin TX
Jack W. Moncrief - Austin TX

A61M 500

128213A

A process for the removal of toxins from the body in a continuous manner while the patient is totally ambulatory. The process involves the infusion of a dialysate fluid under prescribed conditions into the peritoneal cavity. The toxic solutes are transported across the peritoneum membrane into the dialysate fluid by the natural processes of diffusion and convection. The dialysate fluid and the toxins are then removed after a prescribed residence phase. Apparatus includes an indwelling balloon catheter surgically implanted within the peritoneal cavity of a patient, a dacron cuff surgically attached to the abdominal wall, and an external quick connect coupling attached to the catheter. Apparatus may also include a wearable microbiological filter unit for reducing the risk of peritonitis during infusion of dialysate fluid.

4661092, Apr 28, 1987

Dec 9, 1983

6/559783

Robert P. Popovich - Austin TX
Jack W. Moncrief - Austin TX

A61M 3700

604 26

A process for the treatment of hypoxia is provided. The process involves the infusion of highly oxygenated perfluoro-chemicals into the peritoneal cavity of a patient, for oxygen transport into the body and carbon dioxide transport out of the body. The oxygenated perfluorocarbons are subsequently removed from the peritoneal cavity. The infusion and removal can be on a continuous or intermittent basis.

4673385, Jun 16, 1987

Dec 22, 1986

6/946104

Robert P. Popovich - Austin TX
Jack W. Moncrief - Austin TX

A61M 100

604 28

A process to remove large molecules from the body involves infusion of a plasmate solution containing a vasodialating drug into the peritoneal cavity and subsequent drainage on a prescribed schedule.