DR. J. HAROLD HELDERMAN, MD
Osteopathic Medicine at South, Nashville, TN
License number
Tennessee MD19446
Category
Osteopathic Medicine
Type
Nephrology
Address
Address
1161 South St S-3223 MCN, Nashville, TN 37232
Phone
(615) 322-6976
(615) 343-2605 (Fax)
(615) 343-2605 (Fax)
Personal information
See more information about J. HAROLD HELDERMAN at radaris.comName
Address
Phone
Nashville, TN
Organization information
See more information about J. HAROLD HELDERMAN at bizstanding.comJ Harold Helderman MD
1161 21 Ave S, Nashville, TN 37232
Industry:
Internist
Phone:
(615) 343-7609 (Phone)
J Harold Harold Helderman
J Harold Helderman MD
1113 Chickering Park Dr, Nashville, TN 37215
Categories:
Nephrology Physicians & Surgeons, Physicians & Surgeons
Phone:
(615) 343-7592 (Phone)
Professional information
See more information about J. HAROLD HELDERMAN at trustoria.com
Monocyte-Derived Insulin Receptor Regulatory Factor
Monocyte-Derived Insulin Receptor Regulatory Factor
US Patent:
5371189, Dec 6, 1994
Filed:
Apr 30, 1993
Appl. No.:
8/057161
Inventors:
J. Harold Helderman - Nashville TN
Assignee:
Vanderbilt University - Nashville TN
International Classification:
C07K 1300
US Classification:
530350
Abstract:
The present invention relates to a purified monocyte-derived insulin receptor regulatory factor, which has the biological activity of reducing insulin receptor binding on T-lymphocytes. Additionally, the invention relates to a nucleic acid that codes for the monocyte-derived insulin receptor regulatory factor, a recombinant protein produced therefrom, and an antibody to the factor. The present invention also relates to a method of reducing insulin receptor binding on activated T-lymphocytes, including administration of the protein to a subject.